乘子罚函数分光光度法测定小儿安中磺胺二甲嘧啶和磺胺脒的含量  

SIMULTANEOUS SPECTROPHOTOMETRIC DETERMINATION OF SULFAMETHAZINE AND SULFAMIDINE IN XIAOER AN POWDER BY MULTIPLIER PUNITIVE FUNCTION METHOD

作　　者：刘建华[1] 周明达[1] 文莉[1] 邓凯佳 

机构地区：[1]湖南医科大学基础医学院,湖南长沙410078

出　　处：《华西药学杂志》2000年第6期462-463,共2页West China Journal of Pharmaceutical Sciences

摘　　要：目的 :建立同时测定小儿安中磺胺二甲嘧啶和磺胺含量的方法。方法 :以乘子罚函数法处理多波长分光光度数据。结果 :10份模拟样品测定的平均回收率分别为 10 0 2 1%和 98 34% ,RSD分别为 0 5 1%和 0 6 2 % ,对三个实测样品的测定结果与标准方法一致。结论 :准确度和精密度均符合要求。OBJECTIVE:To develop simultaneous spectro photometric determination method for sulfamethazine and sulfamidine in Xiaoer An powder. METHODS:The multiplier punitive function method be used.RESULTS:The average recovery of sulfamethazine and sulfamidine in samples was 100.21% and 98.34% , RSD were 0.51% and 0.62%,respectively( n =10).The results of determination for three batches of Xiaoer An powder were agreed with those by using standard method.CONCLUSION: Its accuracy and precision are satisfactory.

关 键 词：乘子罚函数法 小儿安 碘胺二甲嘧啶 碘胺脒 

分 类 号：R985[医药卫生—药品] R927.2[医药卫生—药学]