新型非酯型拟除虫菊酯类化合物的合成及其生物活性的研究(Ⅰ)  

Synthesis of Novel Non-ester Pyrethroids and Studies on Their Biologic Activity (Ⅰ)

作　　者：李应福[1] 周长海[2] 

机构地区：[1]安徽大学实验中心,230039 [2]北京农业大学应用化学系

出　　处：《高等学校化学学报》1991年第4期479-481,共3页Chemical Journal of Chinese Universities

摘　　要：传统的拟除虫菊酯类杀虫剂均含有1个酯基。近些年来,相继合成了一些非酯型拟除虫菊酯化合物。在保持分子整体空间结构不变的情况下,用其它功能团替换酯基,已开发出肟醚菊酯、醚菊酯、烃菊酯和酮菊酯等高效低毒、结构简化的杀虫剂,其中醚菊酯已正式作为农药商品。作为拟除虫菊酯类化合物结构变化的新尝试,我们合成了10种非酯型拟除虫菊酯新化合物,它们属于N-芳基-3-甲基-3-(对乙氧基苯基)丁酰胺类化合物,结构如下:Ten N-aryl-3-methyl-3-(p-ethoxyphenyl)butyramide were synthesized and screened as new pyrethroids. The structures of the compounds were confirmed by 1H NMR, IR and elemental analysis. All of the compounds showed a moderately insecticidal activity and a knockdown effect against house-flies. For different compounds, the mortality is about 5%~30% and the knockdown percent is about 10%~42. 5% at the dose of 0. 952 μg/housefly.

关 键 词：拟除虫菊酯 非酯型 生物活性 

分 类 号：TQ453.292[化学工程—农药化工]