寒冷条件下大鼠血浆及不同脑区中亮氨酸-脑啡肽、环一磷酸腺苷等含量变化的影响  

Effects of L-EK and cAMP of plasma and different regions in the process of cold stimulations in rats

作　　者：薛秀兰[1] 曹惠君[1] 

机构地区：[1]佳木斯大学基础医学院病生教研室

出　　处：《黑龙江医药科学》2000年第6期1-2,共2页Heilongjiang Medicine and Pharmacy

摘　　要：目的：旨在研究不同低温条件下，这些物质含量变化及影响变化的机制，为内分泌及低温领域提供一定的理论基础。方法：本实验采用放射免疫法对36只大鼠在不同低温环境中亮氨酸－脑啡肽(L-EK)、环一磷酸腺苷(cAMP)、CA2+及Mg2+含量进行观察。结果和结论：实验各组与对照组相比，L-EK、cAMP、Ca2+及Mg2+差异具有显著性(P<0.01)。提示：在寒冷刺激过程中L-EK、cAMP、Ca2+及Mg2+参与体温调节。Objective: In order to study the changes of L-EK and cAMP inplasma and different brain regions and their mechanisms in different hypothermia mice to supply a theoretical basis for study of neuroendocrinclogy and hypothermia fields. Methods: L-EK, cAMP, Ca2+ and Mg2+ of plasma and different regions were observed by RIA and atom aborption methods. Results: and Conclusions: Compared with control, L-EK, cAMP, Ca2+ and Mg2+ in the experimental groups were much increased (P<0.01),and they might be concerned with body temperature regulation.

关 键 词：寒冷 亮氨酸-脑啡肽 环一磷腺苷 CAMP 

分 类 号：R339.55[医药卫生—人体生理学] R363.123[医药卫生—基础医学]