基础胰岛素与预混胰岛素控制围手术期血糖的疗效与安全性临床比较  

The Clinical Comparison of Control Efficacy and Safety of Perioperative Period of Blood Glucose by Basal Insulin and Premixed Insulin

作　　者：李洁[1] 黄春[2] 黄志杰[2] 冼上福[3] 许淑贤[1] 

机构地区：[1]湛江中心人民医院内分泌科,广东湛江524037 [2]湛江中心人民医院肝胆外科,广东湛江524037 [3]湛江中心人民医院普通外科,广东湛江524037

出　　处：《中国医药指南》2014年第1期3-5,共3页Guide of China Medicine

基　　金：湛江中心人民医院青年科研基金项目2012年

摘　　要：目的探讨基础胰岛素与预混胰岛素控制围手术期血糖的疗效与安全性临床比较情况。方法分析我院80例择期中、大型手术2型糖尿病患者临床资料,依据围手术期降糖方案不同进行临床分组,对照组(预混胰岛素组)40例和观察组(基础胰岛素组)40例。结果观察组糖尿病患者三餐餐前、餐后2 h、睡前22时及凌晨3时血糖、血糖达标时间、每天胰岛素用量、低血糖发生率、切口感染或延迟愈合率均明显低于对照组,P<0.05,差异均有统计学意义。结论基础胰岛素控制围手术期血糖是一种安全、有效、快速、平稳的胰岛素降糖方案,可作为糖尿病患者围手术期胰岛素治疗方案进行推广。Objective To approach the clinical comparison of control efficacy and safety of perioperative period of blood glucose by basal insulin and premixed insulin. Method To analyze 80 cases clinical data of 2 DM patients undergoing elective operation in our hospital, which was to be divided into control group （premixed insulin group） 40 cases and observation group （basal insulin group） 40 cases. Result The Before the meal, 2 hours after meals of Three meals, before going to bed at 22 and at 3 in the morning the blood sugar, recovery time, daily insulin dosage, incidence of hypoglycemia, Incision s infection or delayed healing rate of DM patients of observation group were lower than control group, P〈0.05,the difference were statistical significance. Conclusion The basal insulin to control blood glucose during peri operation was Insulin therapy is safe and effective, fast, stable, which was was to be used for Diabetic patients with peri operation period of insulin therapy.

关 键 词：基础胰岛素 预混胰岛素 围手术期 血糖 安全性 

分 类 号：R587.1[医药卫生—内分泌]