特发性颅内高压的影像学研究  

Neuroimaging study of idiopathic intracranial hypertension

作　　者：包庆武 张刚[2] 姜红[2] 刘晓亮[2] 岳凤斌[2] 谢海柱[2] 高波[2] 

机构地区：[1]山东省烟台市福山区人民医院影像科,山东烟台265500 [2]山东省烟台毓璜顶医院影像科,山东烟台264000

出　　处：《医学影像学杂志》2013年第12期1877-1881,共5页Journal of Medical Imaging

摘　　要：目的研究特发性颅内高压（IIH）的可靠影像学征象及与临床症状的关系，提高对该病的认识。方法研究2008年7月～2012年12月有完整临床、影像学资料的20例IIH患者，并以同期20例正常志愿者作为对照组。由2位有经验的神经放射医生共同评价影像学异常，包括垂体及蝶鞍形态、脑室形态及视神经鞘形态。结果空蝶鞍/部分空蝶鞍和视神经鞘扩张都具有较高的敏感性（分别为75％、80％和75％）和特异性（分别为95％、75％和80％）；2组之间Evans指数、双侧麦氏腔长宽比及OND均无统计学差异（P〉O．05），垂体腺高度及深度、双侧ONSD均有统计学显著性差异（Pd0．01）。结论空蝶鞍和视神经鞘扩张是IIH的可靠影像学征象。正确认识IIH的影像学表现对其早期诊断和治疗具有重要价值。Objective To establish the characteristic neuroimaging features of idiopathic intracranial hypertension （IIH）. Methods Twenty IIH patients as well as age-, sex-and body mass index （BMI）-matched controls underwent conventional cranial and orbit MRI examinations, followed by assessment of optic nerve sheaths, pituitary gland, ventricles and Meck el＇s cave. Imaging findings were also correlated with cerebrospinal fluid （CSF） opening pressures and clinical symptom. Results Empty sella and optic nerve sheath distension were identified as reliable imaging signs in IIH. No abnormalities of the lateral ventricles were observed. Clinical symptoms did not correlate with an increase in lumbar opening pressure. Con clusion Empty sella and optic nerve sheath distension were reliable diagnostic signs for IIH.

关 键 词：特发性颅内高压 假性脑瘤 头痛 颅内压 磁共振成像 

分 类 号：R445.2[医药卫生—影像医学与核医学] R742[医药卫生—诊断学]