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作 者:顾亚律[1] 陆信[1] 王颖[1] 杨立民[1] 郝金钢[1] 秦靖婷
机构地区:[1]昆明医科大学第二附属医院放射科,云南昆明650101
出 处:《昆明医科大学学报》2013年第12期105-109,共5页Journal of Kunming Medical University
基 金:云南省卫生厅内设研究机构基金资助项目(2010NS052)
摘 要:目的探讨肺气肿多层螺旋CT(MSCT)形态学与肺功能(PFT)指标的相关性.方法随机选取33例有慢性阻塞性肺疾病(COPD)临床表现者,1周内完成CT和PFT检查.MSCT深吸气末扫描全肺,后处理工作站中定量测定肺密度、肺径线、肺容积共12项形态学指标,并与肺功能指标行相关性分析.结果 FEV1.0%与右上肺密度(r=0.391,P=0.048)、右下肺密度(r=0.465,P=0.038)、平均肺密度(r=0.576,P=0.025)、全肺容积(r=0.471,P=0.043)、右上肺容积(r=0.413,P=0.049);FEV1.0/FVC与左下肺密度(r=0.392,P=0.024)、平均肺密度(r=0.703,P=0.000)、全肺横径(r=0.521,P=0.02)、右上肺最大横径(r=0.627,P=0.001)、全肺容积(r=0.549,P=0.01)具有相关性;FVC与右上肺最大横径(r=0.378,P=0.032)、右肺最大横径(r=0.349,P=0.037);TLC与平均肺密度(r=0.523,P=0.032)、右上肺最大横径(r=0.454,P=0.045)、全肺容积(r=0.628,P=0.001)、右肺容积(r=0.492,P=0.035)具有相关性.结论 MSCT肺形态学定量指标在诊断、评估肺气肿患者中具有良好的临床应用价值.Objective To discuss the correlation between MSCT morphological index of emphysema and pulmonary function test (PFT) indexes. Mothods We randomly selected 33 cases with chronic obstructive pulmonary disease (COPD) , and conducted CT and PFT in a week. The whole lung was scanned by MSCT at the end of deep aspiration, and the post-processing workstation was used for quantitative determination of a total of 12 morphological indexes, including the density of lung, pulmonary diameter hne, lung volume, and etc, then their correlation with lung function index was analyzed. Results FEV1.0% had correlation with upper right lung density (r = 0.391, P = 0.591), lower right lung density (r = 0.465, P = 0.038), the mean lung density (r = 0.576, P= 0.576), and total lung capacity (r= 0.471, P= 0.471), upper right lung volume (r= 0.413, P= 0.049) . FEV1.0 / FVC had correlation with left lower lung density (r = 0.392, P = 0.024), the mean lung density (r = 0.703, P = 0.000) , total lung transverse diameter (r = 0.521, P = 0.521) , upper right lung maximum transverse diameter (r = 0.627, P = 0.627), and total lung capacity (r = 0.549, P = 0.549) correlation. FVC had correlation with upper right lung maximum transverse diameter (r = 0.378, P = 0.378) , characterized by maximum transverse diameter (r = 0.349, P = 0.037) . TLC had correlation with mean lung density (r = 0.523, P = 0.523), upper right lung maximum transverse diameter (r = 0.454, P = 0.454), and total lung capacity (r= 0.628, P = 0.001) , the right lung volume (r = 0.492, P = 0.492) . Conclusion MSCT lung morphology quantitative indicators have good clinical application value in the diagnosis and assessment of emphysema patients.
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