氯硝柳胺的环境行为研究进展  

Progress of niclosamide environmental fate study

作　　者：贾悦[1] 戴建荣[1] 

机构地区：[1]江苏省血吸虫病防治研究所、卫生部寄生虫病预防与控制技术重点实验室、农业部杀虫剂药效评价中心,无锡214064

出　　处：《中国人兽共患病学报》2013年第12期1203-1207,1211,共6页Chinese Journal of Zoonoses

基　　金：国家自然科学基金(No.81071379);国家科技支撑项目(No.2009BAI78B06);江苏省卫生厅医学领军人才项目(No.LJ2011032)联合资助~~

摘　　要：氯硝柳胺是我国血吸虫病流行疫区现场广泛使用的杀螺药物,在血吸虫病防治领域发挥了巨大作用。但其对非目标生物的毒性以及是否会对生态环境产生影响,已引起学者广泛的关注。为此本文概述了氯硝柳胺在水-土壤系统中的降解、吸附等环境行为以及在生物体内的代谢行为,以期为其生态环境风险评价提供参考依据。As a widely used mollusicicide in the schistosomiasis endemic areas, niclosamide has played a critical role in the control of schistosomiasis in China. However, its toxicity to the non-target organisms and the impact on the ecological envi- ronment has been widely concerned. This review is mainly on the discussion of degradation and adsorption of niclosamide in the water-soil system and the metabolism in the organisms. All of these could provide the reference evidence for the ecological envi- ronment risk assessment.

关 键 词：氯硝柳胺 降解 吸附 代谢 

分 类 号：R978.6[医药卫生—药品]