慢性乙型肝炎合并非酒精性脂肪肝患者空腹血糖测定的临床意义  

Clinical Significance of the Determination of Fasting Blood Glucose of the Patients with Chronic Hepatitis B Complicated by Nonalcoholic Fatty Liver Disease

作　　者：周淑贤[1] 李颖莉[1] 陈萍[1] 郭柳薇[1] 欧锦溪[1] 关海天[1] 

机构地区：[1]广西医科大学第七附属医院,广西梧州543000

出　　处：《中外医疗》2013年第33期3-3,5,共2页China & Foreign Medical Treatment

摘　　要：目的探讨慢性乙型肝炎合并非酒精性脂肪肝患者空腹血糖(GLU)测定的临床意义。方法选择慢性乙型肝炎患者79例,其中单纯慢性乙型肝炎(MCHB)31例,慢性乙型肝炎合并非酒精性脂肪肝(MCHB+NAFLD)48例,正常对照者(N.C)67例,通过四表格χ2检验、方差分析ANOV及两两分析探讨各组与空腹血糖相关性。结果 N.C组、MCHB组、MCHB+NAFLD组,测得各组空腹GLU差异有统计学意义(P<0.01),MCHB+NAFLD患者的空腹血糖升高率明显高于MCHB患者及正常对照组(P<0.05)。结论慢性乙型肝炎合并非酒精性脂肪肝患者需要密切监测空腹血糖,这是防治脂肪肝的重要措施。Objective To discuss the clinical significance of metLsuring fasting blood glucose（GLU） for patients with both chronic hepatitis B and nonalcoholic fatty liver disease. Methods With the selection of 79 cases of chronic hepatitis B, including 31 cases of chronic hepatitis B（MCHB）, 48 cases of both chronic hepatitis B and nonalcoholic fatty liver disease （MCHB ＋ NAFLD）, 67 cas- es of normal controls （N.C）, examined by four formx2, analysis of variance on ANOV and pairwise comparison, the correlation be- tween each group and fasting blood glucose was discussed. Results There was significant difference in fasting blood glucose be- tween Group N.C, Group MCHB and Group MCHB＋NAFLD （P〈O.O1）. The rising rate of fasting blood glucose in patients with MCHB＋NAFLD was significantly higher than that in patients with MCHB and in normal controls （P〈0.05）. Conclusion Monitoring fasting blood glucose closely is necessary for patients with both chronic hepatitis B and nonalcoholic fatty liver disease, which is an important measure for preventing and treating fatty liver disease.

关 键 词：慢性乙型肝炎(MCHB) 非酒精性脂肪性肝(NAFLD) 血糖(GLU) 

分 类 号：R512.62[医药卫生—内科学] R575.5[医药卫生—临床医学]