咪达唑仑联合吗啡镇静在机械通气下对急性左心衰竭的疗效观察  

Midazolam combined with morphine sedation curative effect observation of acute left heart failure with mechanical ventilation

作　　者：李燕军[1] 郭云洁 王凤永[1] 

机构地区：[1]广东省南雄市人民医院内科,广东南雄512400

出　　处：《吉林医学》2013年第36期7591-7592,共2页Jilin Medical Journal

摘　　要：目的:讨论咪达挫仑联合吗啡对急性左心衰竭患者机械通气抢救下的镇静效果。方法:选择急性左心衰竭患者90例。分为观察组与对照组,每组45例。对照组给予咪达挫仑静脉推注,观察组给予咪达挫仑联合吗啡。结果:观察组在药物起效时间、镇静时间、停药后苏醒时间、停药至拔管时间及镇静12 h后血气变化和血流动力学变化情况方面均优于对照组(P<0.05)。结论:相比于单独使用咪达挫仑,咪达挫仑联合吗啡具有更好的镇静效果,值得在临床中广泛使用。Objective To discuss the midazolam combined with morphine on acute left heart failure patients under mechanical ventilation in the treatment of the sedative effect.Methods The patients with acute left heart failure in 90 cases.Divided into observation group and control group,45 cases each group.The control group was given midazolam intravenous injection,the observation group was given midazolam combined with morphine.Results To observe the changes of blood gas and hemodynamics changes in drag onset time,calm time,after stopping drug,stop drug recovery time to extubation time and calm after 12 h were better than the control group（P 〈 0.05）.Conclusion Compared to the use of midazolam alone amounted to defeat him,midazolam combined with morphine has better sedation effect, it is widely used in clinical.

关 键 词：ICU 急性左心室衰竭 机械通气 镇静效果 

分 类 号：R541.6[医药卫生—心血管疾病]