糖尿病肢体动脉闭塞症不同中医证型炎症指标比较  

Comparison of Inflammatory Markers of Different TCM Syndrome Types of Diabetic Limb Artery Occlusion

作　　者：许永楷[1] 赵波[1] 陈柏楠[1] 

机构地区：[1]山东中医药大学附属医院周围血管病科,济南250011

出　　处：《中国中西医结合外科杂志》2013年第6期630-632,共3页Chinese Journal of Surgery of Integrated Traditional and Western Medicine

基　　金：山东省中医药科技发展计划项目(2009Z004-2);山东省泰山学者建设工程专项经费资助

摘　　要：目的:观察糖尿病肢体动脉闭塞症湿热下注证患者炎症指标与血瘀证炎症指标的变化特点。方法:对30例糖尿病肢体动脉闭塞症湿热下注证和30例血瘀证患者采用放射免疫法检测白介素1(IL-1)、肿瘤坏死因子(TNF)水平,采用免疫比浊散射法检测超敏C反应蛋白(Hs-CRP)水平,采用生物酶法测定检测脂蛋白(α)(LP(α))水平。结果:湿热下注证Hs-CRP高于血瘀证患者(P<0.01),IL-1、TNF、LP(α)与血瘀证患者比较,差异无统计学意义(P>0.05)。结论:超敏C反应蛋白可作为糖尿病肢体动脉闭塞症湿热下注证的微观辨证参考。Objective To observe the characteristics of patients＇ inflammatory markers of diabetic limb ar- tery occlusion（DLAO） between downward flow of damp-heat and blood stasis syndromes. Methods In 30 pa- tients with Downward flow of damp-heat syndrome and 30 patients with Blood stasis syndrome, interleukin 1 （1L-1） and tumor necrosis factor （TNF） were detected by RIA method, hypersensitive c-reactive protein （Hs CRP） was measured by scatter turbidimetry, lipoprotein （alpha） （LP （alpha）） was determinated by enzymatic tech- nology. Results Hs CRP levels of Downward flow of damp-heat syndrome were higher than that of Blood sta- sis syndrome（P 〈 0.01）. There was no statistically significant difference in IL - 1, TNF and LP （alpha）of the Downward flow of damp-heat syndrome compared with Blood stasis syndrome（P 〉 0.05）. Conclusion Hs CRP can be taken as a reference to the microcosmic syndrome differentiation of the Downward flow of damp-heat syndrome patients of DLAO.

关 键 词：糖尿病肢体动脉闭塞症 湿热下注证 血瘀证 炎症指标 

分 类 号：R654.4[医药卫生—外科学]