健脾化痰活血颗粒治疗瘀血阻络型肝炎肝硬化临床研究  

Clinical study on Huatan Huoxue Granula in treatment of hepatitis cirrhosis with static blood blocking collaterals syndrome

作　　者：郭彦敏[1] 徐光福[2] 

机构地区：[1]山东中医药大学附属日照市中医医院,山东日照276800 [2]北京中医药大学东直门医院,北京100700

出　　处：《现代中西医结合杂志》2014年第3期242-244,共3页Modern Journal of Integrated Traditional Chinese and Western Medicine

摘　　要：目的探讨中药化痰活血颗粒治疗肝炎肝硬化的临床疗效。方法 90例瘀血阻络型肝炎肝硬化患者随机分为2组,治疗组45例予化痰活血颗粒治疗,对照组45例予大黄虫丸治疗,治疗后观察2组患者症状、体征、影像学变化,检测肝功能。结果治疗组总有效率93%,对照组78%,2组比较有显著性差异(P<0.05)。治疗组肝功改善明显优于对照组(P<0.05)。治疗组临床症状和体征(除肋下积块)改善显著优于对照组(P均<0.05或0.01)。结论化痰活血颗粒对肝炎肝硬化患者具有良好的治疗效果,能够改善肝功能,缓解临床症状和体征。Objective It is to approach the clinical effect of Huatan Huoxue Granula in treating the patients with hepatitis cirrhosis. Methods 90 hepatitis cirrhosis patients with static blood blocking collaterals syndrome were divided into two groups, 45 patients in treatment group were treated with Huatan Huoxue Granula, and 45 patients in control group were treated with Dahuang Zhechong pills, all the patients in two groups were both treated for 6 months, the changes of symptoms,signs and im- agery were observed, and hepatic function were examined before and after treatment. Results The total effect ratio were 93% in treatment group and 78% in control group, there was significant difference between two groups （P 〈0.05）. The improve- ment of hepatic function in treatment group was better than that in control group, there was significant difference between two groups （ P 〈 0.05 ）. The melioration of clinical symptoms and signs （ except of the block for flank） in treatment group was bet- ter than that in control group （ all P 〈 0.05）. Conclusion Huatan Huoxue Granula has satisfactory curative effect in treatment of patients with hepatitis cirrhosis, it can ameliorate the symptom, signs and liver function.

关 键 词：肝炎肝硬化 化痰活血颗粒 瘀血阻络型 

分 类 号：R657.31[医药卫生—外科学]