美容性纹身和染发与结缔组织病的关系  

Cosmetic Tattoo and Hair-Dyes Exposures Associated with Systemic Connective Tissue Diseases

作　　者：沈敏[1] 焦洋[2] 龚瑜林[1,3] 刘艳[1,4] 

机构地区：[1]中国医学科学院北京协和医学院北京协和医院风湿免疫科风湿免疫病学教育部重点实验室,北京100730 [2]中国医学科学院北京协和医学院北京协和医院普通内科,北京100730 [3]内蒙古医科大学第一附属医院风湿免疫科,呼和浩特010050 [4]内蒙古包钢医院风湿免疫科,包头014010

出　　处：《中华临床免疫和变态反应杂志》2013年第4期330-334,共5页Chinese Journal of Allergy & Clinical Immunology

基　　金：中华医学会临床医学科研专项资金(12040760376);北京协和医院青年科研基金(2010103)

摘　　要：目的研究美容性纹身和染发与弥漫性结缔组织病的关系。方法对2012年12月至2013年3月北京协和医院同一名风湿免疫科医师门诊接诊的592例女性患者进行回顾性调查,收集其美容性纹身或染发的相关情况与病史,分析美容性纹身和染发与弥漫性结缔组织病的关系。结果 592例女性患者中有77例接受美容性纹身,平均纹身时间(13.5±7.5)年;121例染发,平均染发时间(7.1±5.8)年。比较美容性纹身与没有美容性纹身者、染发与未染发者患弥漫性结缔组织病的发生率,差异均无统计学意义(70.1%vs.66.4%,73.6%vs.65.2%,均P>0.05)。弥漫性结缔组织病与非结缔组织病患者比较,接受美容性纹身或染发比例差异亦无统计学意义(13.6%vs.11.7%,22.5%vs.16.3%,均P>0.05)。结论尽管美容性纹身和染发者弥漫性结缔组织病的发生率高于未接受美容性纹身和染发者,且女性弥漫性结缔组织病患者接受美容性纹身和染发的比例高于非弥漫性结缔组织病患者,但差异并无统计学意义。需进行更加严格的大样本病例对照研究或队列研究以进一步证实美容性纹身和染发与弥漫性结缔组织病的相关性。To explore the risk factors, including cosmetic tattoo and hair dyes, that have been suggested to be associated with the deveXopment of systemic connective tissue diseases. Methods The study was comprised of 592 women who visited the out-patient clinic of a rheumatologist, from December 2012 to March 2013. A questionnaire including questions about exposure to cosmetic tattoo and hair dyes, and structured interview were conducted. Results In total, 77 cases had exposures to cosmetic tattoo and 121 cases ever used hair dyes. The incidence difference of systemic connective tissue diseases between cases exposed and not-exposed to cosmetic tattoo and hair dyes was not statistically significant （70. 1% vs. 66.4%, 73.6% vs. 65.2%, separately）, P 〉0.05. There was no significant difference in exposures to cosmetic tattoo and hair dyes between patients with and without systemic connective tissue diseases （ 13.6% vs. 11.7%, 22. 5% vs. 16. 3%, separately）, P 〉0. 05. Conclusion Neither exposure to cosmetic tattoo nor exposure to hair dyes is associated with systemic connective tissue diseases. Further cohort and case-control studies are needed to confirm the environmental risk factors for developing systemic connective tissue diseases.

关 键 词：美容性纹身 结缔组织病 危险因素 

分 类 号：R593.2[医药卫生—内科学]