蓝氏贾第鞭毛虫细胞骨架蛋白的分子生物学研究进展  

Advances in molecular biology research on cytoskeletal proteins of Giardia lamblia

作　　者：余源[1] 李巍伟[1] 陈阳[1] 王洋[1] 赵丽娜[1] 沈海娥[1] 田喜凤[1] 

机构地区：[1]河北联合大学生命科学学院,河北唐山063000

出　　处：《中国病原生物学杂志》2013年第12期1140-1141,1147,共3页Journal of Pathogen Biology

基　　金：国家自然科学基金项目(No.30970313);唐山市科技支持计划项目(No.12140209A-33)

摘　　要：蓝氏贾第鞭毛虫作为真核生物的模型,越来越受到广大生物学学者的重视,贾第虫借助细胞骨架蛋白附着于宿主肠上皮细胞,导致贾第虫病。将蓝氏贾第鞭毛虫细胞骨架蛋白成分作为新药物开发靶点的研究与日俱增。本文综述了蓝氏贾第鞭毛虫细胞骨架蛋白的分子生物学研究方法及最新进展,为新药物的开发及贾第虫骨架蛋白的进一步研究提供有价值的资料。Scholars have increasingly focused on Giardia lamblia as a model of a eukaryotic system. G. lamblia uses cytoskeletal proteins to attach to a host＇s intestinal epithelial cells, causing giardiasis. Cytoskeletal protein components of G. lamblia are increasingly being studied to develop targets for new drugs. This review describes molecular biology ap- proaches to the study of the cytoskeletal proteins of G. lamblia and the latest advances in those approaches, providing valuable information for the development of new drugs and further study of the cytoskeletal proteins of G. lamblia.

关 键 词：蓝氏贾第鞭毛虫 骨架蛋白 蛋白质组学 比较基因组学 综述 

分 类 号：R382.2[医药卫生—医学寄生虫学]