肾血流阻力指数与体外循环手术急性肾损害的相关性  

Correlation between renal blood flow resistance index and acute kidney injury after cardiopulmonary bypass

作　　者：刘慧[1] 付勇 李明星[1] 陈晓梅[1] 于风旭 邓明彬 

机构地区：[1]泸州医学院附属医院超声诊断科 [2]胸心外科,四川泸州646000

出　　处：《中国医学影像技术》2014年第1期95-98,共4页Chinese Journal of Medical Imaging Technology

基　　金：四川省卫生厅基金资助项目(110347);四川省医学会基金资助项目(SHD11-18);泸州医学院基金资助项目([2010]108)

摘　　要：目的探讨肾血流阻力指数(RI)与体外循环手术(CPB)后急性肾功能损害(AKI)的相关性。方法对因心脏疾病接受CPB的14例患者,应用CDFI检测术前、术后1、2、4、8、16、24h时主肾动脉、肾段动脉阻力指数(RI);同时检测尿素氮(Urea)、尿酸(UA)、肌酐(Crea),评价肾功能;对所有数据进行统计学分析。结果与术前相比,术后1、2、8、16h主肾动脉RI、肾段动脉RI均明显增高(P均<0.05)。术前及术后各时间点主肾动脉RI与Urea、UA、Crea均呈正相关(r=0.390,0.355,0.426,P均<0.05);肾段动脉RI与Crea呈正相关(r=0.316,P<0.05)。结论主肾动脉、肾段动脉RI可作为评估CPB术后发生AKI的指标。Objective To explore the relationship between renal blood flow resistance index （RI） and acute kidney injury （AKI） caused by eardiopulmonary bypass （CPB）. Methods Totally 14 patients with heart disease who accepted CPB were included. RI of the main renal artery and segmental renal artery of all cases were monitored with CDFI preoperatively and 1, 2, 4, 8, 16, 24 h after operation. Blood urea nitrogen （Urea）, uric acid （UA） and creatinine （Crea） were measured at the same time for evaluation of renal function. All data were statistically analyzed. Results RI of the main renal artery and of segmental renal artery were both obviously higher than those preoperatively 1, 2, 8, 16 h after operation （all P〈0.05）. Preoperative and postoperative RI of main renal artery positively correlated with Urea, UA and Crea （r=0. 390, 0. 355, 0. 426, respectively, all P〈0.05）, while RI of segmental renal artery positively correlated with Crea （r= 0. 316, P〈 0.05）. Conclusion RI of main renal artery and segmental renal artery may be used as reliable indexes for evaluation of AKI after CPB.

关 键 词：超声检查 多普勒 脉冲 肾功能 急性肾损伤 体外循环 阻力指数 

分 类 号：R445.1[医药卫生—影像医学与核医学] R682[医药卫生—诊断学]