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机构地区:[1]四川大学华西医院康复医学中心,成都610041 [2]康复医学四川省重点实验室,成都610041
出 处:《四川大学学报(医学版)》2014年第1期102-106,2,共5页Journal of Sichuan University(Medical Sciences)
基 金:国家自然科学基金(No.30672215和No.81171865)资助
摘 要:骨关节炎和骨质疏松是影响老年人生活质量的两大主要骨与骨关节疾患。两病发病机制不同却又不无联系。近年来,国内外临床诊疗指南所推荐的一系列用于骨关节炎和骨质疏松的物理治疗方式,成为当前关注的热点问题,但其应用仍存在争议。这主要体现在:目前关于物理治疗对骨关节炎和骨质疏松的研究量较少、质量较差,临床结局测量指标不一致;而一些动物学研究的结果又难以转化为临床实践或在人体试验中证实。因此,物理治疗骨关节炎和骨质疏松研究的方向应是注重科学设计动物实验和临床试验,联合开展基础和临床研究,探讨物理治疗对骨关节炎和骨质疏松的作用机制、临床疗效和安全性,并注重基础研究和临床研究的相互转化;根据综合康复治疗的理念,注重不同物理因子及其参数之间的相互作用和相互配合,寻找最佳的治疗方案,努力为骨质疏松和骨关节炎患者解决病痛。Osteoarthritis (OA) and osteoporosis (OP) are primary bone and joint diseases affecting the quality of life of old people. The two diseases are different in pathogenesis but are closely associated from each other. Recent clinical guidelines have recommended physical therapies for OA and OP, which have attracted attentions and debates. This is because there is a lack of quality research into this topic. The available studies have used different measurements, and many have not been able to obtain evidence from human research apart from animal experiments. There is a need to undertake both animal and human studies with a stringent design so that the clinical efficacy and mechanism of physical therapy as well as its safety for OA and OP can be explored. We also need to pay attention to the interactions between various physical factors in order to find the best solutions in physical therapies for OA and OP.
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