CT引导下单纯性肾囊肿硬化治疗中乙醇浓度监测的应用  

The application of ethanol concentration monitoring in CT-guided sclerotherapy for simple renal cysts

作　　者：曾利川 杜勇[1] 杨汉丰[1] 李杨[1] 徐晓雪[1] 任逢春[1] 孙凤[1] 牛翔科 肖应权[1] 

机构地区：[1]四川南充川北医学院附属医院CT介入室,医学影像四川省重点实验室,637000

出　　处：《介入放射学杂志》2014年第1期46-49,共4页Journal of Interventional Radiology

摘　　要：目的探讨乙醇浓度监测在CT引导下单纯性肾囊肿硬化治疗中的临床应用价值。方法首先测定不同浓度（10％-100％）乙醇CT扫描值；临床研究中，回顾性分析2006年9月-2012年8月单纯性肾囊肿无水乙醇硬化治疗108例，甲组（40例）未作乙醇浓度监测，乙组（68例）肾囊肿硬化治疗时，监测囊内乙醇浓度变化使囊肿内液体CT值达到-210HU（为无水乙醇测得的CT值）。6个月后根据CT或超声复查结果，对比分析两组疗效。结果实验研究中，CT值与乙醇浓度呈线性相关（r=-0．983，P〈0．05）。临床研究中，甲组完全缓解23例，部分缓解9例，有效率80．0％，乙组完全缓解56例，部分缓解12例，有效率100％，两组完全缓解与有效率差异具有统计学意义（P〈0．05）。结论实验研究显示CT值与乙醇浓度呈线性相关，CT引导下单纯性肾囊肿无水乙醇硬化治疗时．通过监测乙醇浓度可以明显提高治疗效果。Objective To evaluate ethanol concentration monitoring in performing CT- guided sclerotherapy for simple renal cysts. Methods This study consisted of experimental part and clinical part. For the experimental study, different concentrations of ethanol solution （from 10% to 100% at 10% increments） were scanned with CT, and the CT values were determined. The correlation between CT values and ethanol concentrations were analyzed. A total of 108 consecutive patients with simple renal cysts were enrolled in the clinical study. The patients were admitted to authors＇ hospital during the period from Sep. 2009 to Aug. 2012 and received sclerotherapy with ethanol. The patients were divided into group A （n = 40） and group B （n = 68）. During the operation ethanol concentration monitoring was not employed in patients of group A, while ethanol concentration monitoring of the cyst was used in patients of group B. Six months after the treatment, follow-up CT scanning or ultrasound examination were made, and the results were compared between the two groups. Results In the experimental study, a linear correlation existed between the CT values and ethanol concentration （r = -0.983, P 〈 0.05）. In the clinical study, the complete regression rate, partial regression rate and overall success rate of group A were 57.5% （23/40）, 22.5% （9/40） and 80% （32/ 40） respectively, and those of group B were 82.4%（56/68）, 17.6%（12/68） and 100%（68/68） respectively. The differences in complete regression rate and overall success rate between group A and group B were statistically significant （P 〈 0.05）. Conclusion The experimental study indicates that a linear correlationexists between CT values and ethanol concentrations. With the help of ethanol concentration monitoring, CT - guided sclerotherapy can significantly improve the therapeutic effect for simple renalcysts.

关 键 词：肾囊肿 乙醇 硬化治疗 介入放射学 

分 类 号：R692.9[医药卫生—泌尿科学]