弓形虫感染对宿主中枢神经系统的影响  

Effects of Toxoplasma gondii Infection on the Central Nervous System of Host

作　　者：汪涛[1,2] 余辉[1] 王中平 

机构地区：[1]九江学院基础医学院病原生物学教研室,江西九江332000 [2]江西省系统生物学临床应用重点实验室,江西九江332000

出　　处：《动物医学进展》2014年第1期98-101,共4页Progress In Veterinary Medicine

基　　金：江西省教育厅科技项目(GJJ12624);九江学院博士科研启动项目(8870909)

摘　　要：弓形虫是一种世界范围内广泛分布的机会性致病原虫,能感染包括人在内的所有温血动物,能引起人兽共患的弓形虫病,严重威胁着人类健康和畜牧业生产。目前,脑内弓形虫感染越来越受到重视,论文重点阐述了弓形虫从感染到进入中枢神经系统后感染急性阶段逐渐向慢性阶段转化的整个过程中和中枢神经系统之间的相互作用,并对其导致的相关神经系统症状进行了简要概述,旨在为进一步深入理解弓形虫和宿主之间的关系提供一定的参考,在将来的研究中弓形虫和中枢神经系统之间相互作用的机制也会被进一步揭示。Toxoplasma gondii is widely distributed opportunistic pathogen that can infect all warm-blooded animals,including human and cause zoonotic toxoplasmosis, seriously threating human health and livestock production. At present, cerebral toxoplasmosis gets more and more attention. The article focused on the in- teraction of Toxoplasma gondii and the central nervous system （CNS） after Toxoplasma gondii entering the central nervous system, in the entire process, from acute phase of infection to chronic phase and related neurological symptoms caused by their interaction. It will provide a valuable reference for fully understand- ing host-pathogen relationship. In future research,the mechanism of interaction of Toxoplasma gondii and the central nervous system will be further disclosed.

关 键 词：弓形虫 中枢神经系统 相互作用 

分 类 号：S852.72[农业科学—基础兽医学] S852[农业科学—兽医学]