胰腺型、经典型鸭1型甲肝病毒对雏鸭的致病性差异  

Different Pathogenicity of Duck Hepatitis A Virus 1 Between Pancreatitis-type and Classical Duckling

作　　者：陈珍[1,2] 傅秋玲[1,2] 陈红梅[1,2] 傅光华[1,2] 施少华[1,2] 程龙飞[1,2] 万春和[1,2] 林建生[1,2] 黄瑜[1,2] 

机构地区：[1]福建省农业科学院畜牧兽医研究所,福建福州350013 [2]福建省畜禽疫病防治工程技术研究中心,福建福州350013

出　　处：《福建农业学报》2013年第10期939-942,共4页Fujian Journal of Agricultural Sciences

基　　金：新世纪"百千万人才工程"国家级人选科研补助资金(NCNCMTPC-2009);福建省自然科学基金(2011J01113);福建省农业科学院科技下乡"双百"行动项目(sbmx1302-3)

摘　　要：为明确胰腺型鸭1型甲肝病毒(DHAV-1)和经典型DHAV-1对不同品种雏鸭的致病性,以胰腺型DHAV-1和经典型DHAV-1分别感染7、14、21、28、35d番鸭、半番鸭、樱桃谷鸭和麻鸭,结果表明番鸭对胰腺型DHAV-1最易感,半番鸭和樱桃谷鸭次之,麻鸭最不易感;而樱桃谷鸭对经典型DHAV-1最易感,番鸭次之;感染胰腺型DHAV-1的番鸭、半番鸭胰腺出血、明显发黄,肝脏未见出血。表明胰腺型鸭1型甲肝病毒、经典DHAV-1在易感宿主、组织嗜性和特征肉眼病变上均存在明显差异。A duck hepatitis A virus 1 （DHAV-1）, designated pancreatitis-type DHAV-1, has been isolated from Muscovy ducklings with yellow or hemorrhagic pancreas. To elucidate different pathogenicity of DHAV-1 infection between pancreatitis-type and classical ducklings, Muscovy duck, mallard duck, Cherry valley duck and Maya duck, raised for 7, 14, 21, 28 and 35 d respectively, were inoculated with pancreatitis-type and classical DHAV-1. The results showed that Muscovy duck was the most sensitive to pancreatitis-type DHAV-1, followed by mallard duck and Cherry valley duck, and the Maya duck was the lowest. However, Cherry valley duck was the most sensitive to classical DHAV-1, followed by Muscovy ducks. Hemorrhagic and yellow pancreas was detected in Muscovy duckling and mallard duckling infected with pancreatitis-type DHAV-1, but no hemorrhage in liver. The above indicated that there were obviously different pathogenicity between pancreatitis-type and classical DHAV-1 in sensitive host, and gross lesions.

关 键 词：鸭1型甲肝病毒 胰腺型 致病性 

分 类 号：S852[农业科学—基础兽医学]