体外受精-胚胎移植中未获卵周期临床影响因素的探讨  

The Research about the Related Clinical Features of Failing to Obtain Follicle in IVF-ET

作　　者：张晶[1] 全松[2] 陈雷宁[2] 

机构地区：[1]南华大学附属第一医院妇产科生殖医学中心,湖南衡阳421001 [2]南方医科大学附属南方医院生殖医学中心

出　　处：《中南医学科学杂志》2013年第6期572-575,共4页Medical Science Journal of Central South China

摘　　要：目的分析各因素对体外受精-胚胎移植(IVF-ET)未能获卵的影响,探讨IVF-ET未能获卵可能的原因。方法回顾性收集接受IVF治疗后未获得卵子的70例不孕妇女为未获卵组,140例获得卵子的不孕妇女为获卵组,分析总结其临床资料,对各可能影响获卵的因素进行t检验和多元线性回归分析。结果两组患者年龄、卵巢储卵数、HCG日E2值、LH值比较,差异均有显著性(P<0.05)。经多元线性回归分析,其中HCG日E2值、LH值和左卵巢储卵数对获得卵子数的影响较大。结论年龄、卵巢储卵数、HCG日E2值、LH值对于是否获卵影响较大。IVF-ET周期治疗中,综合分析身高和体重、基础E2与FSH,给与适量的促性腺激素促卵泡生长,能降低未能获卵的发生。Objective To analyze the effect of related factors on the IVF-ET fail to obtain follicle, to explore the possible reasons of unavailable follicle in IVF-ET. Methods Retrospectively collected acceptance of IVF / ICSI treat- ment in 70 patients did not obtain follicle for infertile women, as the not obtain follicle group, 140 cases of infertile women who had obtain follicle as the obtain follicle group, to analyze the factors that may affect our access to follicle with T-test and multiple linear regression analysis. Results Age, the E2 and LH data in the day of HCG injection and the number of fol- licle in reserve of ovary between the two groups had significant difference （ P 〈 0.05 ）. Multivariate linear regression analysis showed that the values of E2 ／ LH and the number of ovarian folicles reserved by the left ovary have larger effects on the number of abtained follicle. Conclusion Age, the number of follicle in reserve of ovary and the E2 and LH data in the Day of HCG injection play an important role in the availability of obtain follicle; In treatment cycle of IVF-ET, combined with height and other factors, have a comprehensive analysis and give an appropriate amount of gonadotropin which can stim- ulate follicle growth to reduce the risk of failure in abtain follicle.

关 键 词：体外受精-胚胎移植 获卵数 年龄 储备卵泡 雌激素 

分 类 号：R71[医药卫生—妇产科学]