中药单体联用抗真菌药物抗耐药白色念珠菌的研究现状  

Research status of natural compounds combine with antifungal agents against drug-resistent Candida albicans

作　　者：万江帆[1] 唐春萍[1] 沈志滨[1] 江涛[1,2] 

机构地区：[1]广东药学院中药学院,广东广州510006 [2]广东药学院动物实验中心,广东广州510006

出　　处：《中国中药杂志》2014年第1期28-33,共6页China Journal of Chinese Materia Medica

基　　金：国家"重大新药创制"科技重大专项(2011ZX09102-007-03);广东省科技厅科技计划项目(2010B030700044;2011A030100013);2010年广东省教育厅高层次人才资助项目;广州市科技局科技计划项目(12A062131631)

摘　　要：近年来,针对耐药白色念珠菌感染的不断出现,有关中药单体联用抗真菌药物对耐药白色念珠菌作用的研究日趋增多。该文重点采用FICI评价法比较多种中药单体与抗真菌药物联用的协同作用,并对目前已阐明的协同机制进行归纳总结。To against the emergence of drug-resistent candidiasis, the studys of synergism of natural compounds combine with antifungal agents in vitro showed a continuous growth in recent years. The paper reviewed recent progresses to compare the synergetic effect by FICI method, and to conclude the synergetic mechanisms which have been confirmed as a reference for futher study.

关 键 词：耐药白色念珠菌 中药单体 协同作用 协同机制 体外实验 

分 类 号：R285[医药卫生—中药学]