基于溶液环境调节理论的黄连解毒汤陶瓷膜微滤过程的预处理研究  

Study of pretreatment on microfiltration of Huanglian Jiedu decoction with ceramic membranes based on solution environment regulation theory

作　　者：李博[1] 张连军[1,2] 郭立玮[1] 付廷明[1] 朱华旭[1] 

机构地区：[1]南京中医药大学中药复方分离工程重点实验室,江苏南京210029 [2]江苏省荣军医院,江苏无锡214035

出　　处：《中国中药杂志》2014年第1期59-64,共6页China Journal of Chinese Materia Medica

基　　金：国家自然科学基金项目(30873449;30973950;81274096);江苏省科技厅产学研联合创新资金--前瞻性研究项目(BY2012036);江苏省科技厅自然科学基金项目(BK2012855)

摘　　要：为了优化黄连解毒汤膜分离前的预处理方式,该文以黄连解毒汤为研究对象,通过不同的预处理方式调节溶液环境及物料流变特征,分别考察不同溶液环境对膜通量、共性高分子物质去除率、指标性成分透过率等指标的影响。研究发现,絮凝时的膜通量最高,指标性成分透过率高(>94.8%),共性高分子物质截留率较高;减压抽滤和调节pH为9时次之;调节pH和絮凝时指标性成分透过率相对较高,膜污染的主要因素为膜堵塞阻力。综合各项指标,以絮凝的预处理效果最佳,调节pH为9时次之。To optimize the pretreatment of Huanglian Jiedu decoction before ceramic membranes and verify the effect of different pretreatments in multiple model system existed in Chinese herb aqueous extract. The solution environment of Huanglian Jiedu decoction was adjusted by different pretreatments. The flux of microfiltration, transmittance of the ingredients and removal rate of common polymers were as indicators to study the effect of different solution environment. It was found that flocculation had higher stable perme- ate flux, followed by vacuuming filtration and adjusting pH to 9. The removal rate of common polymers was comparatively high. The removal rate of protein was slightly lower than the simulated solution. The transmittance of index components were higher when adjust pH and flocculation. Membrane blocking resistance was the major factor in membrane fouling. Based on the above indicators, the effect of flocculation was comparatively significant, followed by adjusting pH to 9.

关 键 词：无机陶瓷膜 预处理 黄连解毒汤 膜通量 溶液环境 

分 类 号：R283[医药卫生—中药学]