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机构地区:[1]解放军第二七三医院骨二科,新疆库尔勒841000
出 处:《解放军医学院学报》2014年第1期81-84,共4页Academic Journal of Chinese PLA Medical School
基 金:全军医药卫生科研项目(CLZ11JB32)~~
摘 要:目的探讨南疆沙漠地区绵羊肢体火器伤后机动转运过程中伤道的细菌学变化,为本地区战伤救治提供理论依据。方法 20只新疆绵羊随机分为实验组及对照组,每组10只,将两组羊后肢制作成火器伤模型。实验组采用机动转运方式后送,对照组不进行后送。于实验点及转运各时间点进行空气培养及体温测量,两组于伤后0、2、4、6、8、12、24 h进行伤道分泌物细菌培养及药敏试验。结果两组空气培养细菌种类主要为G+菌,两组于伤后4 h伤道分泌物细菌培养无细菌生长,伤后6 h两组均开始有细菌生长,分泌物培养为G+菌,而伤后12 h两组均有G+菌及G-菌生长,实验组菌群以G-菌为主,对照组菌群以G+菌为主。实验组于伤后6 h体温开始升高,对照组于伤后12 h体温开始升高,两组菌群均对环丙沙星、呋喃妥因、妥布霉素、复方新诺明药物敏感。结论在南疆沙漠地区机动转运绵羊火器伤伤道细菌以G-菌为主,因此抗生素的使用应结合本地区细菌学特点合理选择。Objective To provide the theoretical basis for the treatment of war wounds by studying the bacteriology in sheep extremity fire-ann injury during transport in desert area of Southern Xinjiang Uyghur Autonomous Region. Methods Twenty sheep from Southern Xinjiang Uyghur Autonomous Region were randomly divided into experimental group and control group (10 in each group). A hind leg fire-arm injury model was established. Sheep in experimental group were evacuated with vehicle and those in control group were not evacuated. The bacteria were cultured in air and the body temperature of sheep was measured at different experiment and evacuation time points. Bacteria from wound secretions were cultured and drug sensitivity was tested in sheep at 0, 2, 4, 6, 8, 12 and 24 h, respectively, after injury. Results The main bacteria cultured in air were Gram-positive. No bacteria were found in wound secretions at 4 h after injury. However, Gram-positive and gram-negative bacteria were observed in 2 groups at 6 and 12 h after injury. The body temperature began to increase in experimental group at 6 h after injury and in control group at 12 h after injury. The bacteria in 2 groups were sensitive to ciprofloxacin, furadantin, tobramicin and trimesulf. Conclusion The main bacteria found in sheep extremity fire-arm injury during transport in desert area of Southern Xinjiang Uyghur Autonomous Region are Gram- negative, antibiotics should thus be rationally used according to the bacteriological features in this area.
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