微生物敏感性检测在肺炎支原体肺炎治疗中的应用  

Application of drug susceptibility test in treatment of mycoplasma pneumonia

作　　者：王敏[1] 康云凯 郑业焕[3] 付光宇[4] 张泉 

机构地区：[1]河南省郑州人民医院呼吸科,450003 [2]河南省郑州人民医院检验科,郑州450003 [3]郑州大学微生物学教研室,郑州450001 [4]郑州大学基础医学院寄生虫学教研室,郑州450001 [5]郑州安图生物工程股份有限公司,郑州450016

出　　处：《检验医学与临床》2014年第1期25-27,共3页Laboratory Medicine and Clinic

摘　　要：目的了解微生物敏感性检测在临床肺炎支原体感染后治疗中的价值,以指导临床合理用药。方法选择肺炎支原体阳性的支原体肺炎患者305例,根据是否经验用药分为A、B两组。A组126例,为经验用药的肺炎支原体感染者;B组179例,为肺炎支原体感染的初诊患者。依据微生物敏感性检测结果用药并观察疗效。结果A组患者对不同类别抗菌药物的耐药性高于B组(P<0.05);两组患者治疗后效果相比,B组有效率明显高于A组(P<0.05)。结论微生物敏感性检测在预防肺炎支原体耐药株的传播及肺炎支原体肺炎的治疗中有重要参考价值,对合理使用抗菌药物具有指导意义。Objective To investigate the value of the drug susceptibility test in the treatment of Mycoplasma pneurnoniae infection to guide clinical rational medication. Methods 305 cases of mycoplasma pneumonia with posi- tive Mycoplasma pneurnoniae were selected and divided into the group A and B according to whether using empirical medication. 126 cases in the group A were Mycoplasrna pneumoniae infection treated by the impirical medication and 179 cases in the group B were the new diagnosis of Myeoplasma pneumoniae infection. The medication was used ac- cording to the results of drug susceptibility test and the curative effects were observed. Results The resistance to dif- ferent antibacterial drugs in the group A was higher than that in the group B, showing statistical difference（P~ 0. 05）. Comparing the curative effects after treatment between the two groups, the effective rate in the group B was significantly higher than that in the group A（P^0.05）. Conclusion The drug susceptibility test has important refer- ence value in the prevention of Myeoplasma pneumoniae resistant strains spread and the effective treatment of myeo- plasma pneumonia, as well as the guidance significance in rational use of antibacterial drugs.

关 键 词：肺炎支原体 治疗 培养 耐药 

分 类 号：R725.631[医药卫生—儿科]