复方黄芪合剂对小鼠免疫功能影响  

Influence of Fufang Huangqi Mixture on Immune Regulation in Mice

作　　者：罗新舟[1] 孙江桥[1] 

机构地区：[1]湖北中医药大学,湖北武汉430065

出　　处：《辽宁中医药大学学报》2014年第1期21-22,共2页Journal of Liaoning University of Traditional Chinese Medicine

摘　　要：目的:观察复方黄芪合剂对小鼠免疫功能的影响。方法:将实验小鼠随机分为复方黄芪合剂高剂量组(24 g·kg-1)、复方黄芪合剂低剂量组(12 g·kg-1)、香菇菌多糖片组(0.03 g·kg-1)和蒸馏水对照组,通过测定药物对小鼠的胸腺和脾脏指数、碳粒廓清吞噬指数(K)及校正吞噬指数(α)和血清溶血素抗体积数的影响,观察复方黄芪合剂对机体免疫功能的影响。结果:复方黄芪合剂可增强小鼠的脾脏指数(P<0.05)及胸腺指数(P<0.01),升高碳粒廓清吞噬指数(P<0.01)及校正吞噬指数(P<0.01),提高血清溶血素抗体积数(P<0.05,P<0.05)。结论:复方黄芪合剂对小鼠的特异性和非特异性免疫功能有促进作用。Objective ： To investigate the influence of Fufang Huangqi Mixture on immune regulation in mice. Method： Mice were divided into five groups. By the effect of the indexes of spleen and thymus, carbon particle clearance swallowing index and the level of serum hemolysin antibody reflected the immune function. Result ： Fufang Huangqi Mixture can enhance the indexes of spleen and thymus, increase the number of K and ot , and improve the level of serum hemolysin antibody. Conclusion ： Fufang Huangqi Mixture can enhance the nonspecific immunity and specific immunity function in mice.

关 键 词：复方黄芪合剂 特异性免疫 非特异性免疫 

分 类 号：R446.63[医药卫生—诊断学]