乙型肝炎肝硬化发病机制特点研究概况  

Research Overview on Pathogenesis Characteristics of Hepatitis-B Cirrhosis

作　　者：石志平[1] 吴同玉[1] 

机构地区：[1]福建中医药大学,福建福州350108

出　　处：《辽宁中医药大学学报》2014年第1期91-94,共4页Journal of Liaoning University of Traditional Chinese Medicine

基　　金：国家自然科学基金青年基金项目(81102559);福建省自然科学基金项目(2011J01215)

摘　　要：肝硬化是临床常见的一种慢性、进行性肝病,由一种或多种病因长期或反复作用形成的弥漫性肝损害,乙型肝炎病毒(HBV)是引起肝硬化主要原因之一。近年来研究表明,肝纤维化或早期肝硬化是可以逆转或延缓进展,阐明乙型病毒肝炎(简称乙肝)肝硬化发病过程中的重要致病因素特点,对预防失代偿期的肝硬化发生和发展成肝癌具有重要意义,中医认为主要与湿热疫毒有关,现代医学在病毒学、免疫学研究基础上,开始着手从遗传易感性方面展开研究。该文就近年来中西医有关乙肝肝硬化发病机制的研究进行概括。Liver cirrhosis is a common clinical chronic and progressive liver disease. It forms liver damage by one or more causes of the long-term or repeated diffuse. Hepatitis B virus （ HBV ） is one of the most important factors to cause cirrhosis of the liver. The research shows that early liver fibrosis or cirrhosis can he reversed or delayed in recent years. It is of great significance to clarify the characteristics of important pathogenic factors in the process of hepatitis B virus cirrhosis of the liver to prevent the happening of the decompensation period of liver cirrhosis and liver cancer. The traditional Chinese medieine（ TCM ） holds that it may associate with heat and damp. The modern medical starts from researching the aspects ot＂ the genetic susceptibility on the basis research in virology and immunology. This paper summarizes the studies of the pathogenesis of hepatitis B cirrhosis of the liver from TCM and modern medicine.

关 键 词：乙型肝炎肝硬化 发病机制 研究概况 

分 类 号：R512.62[医药卫生—内科学] R657.31[医药卫生—临床医学]