丹红注射液上市后医院集中监测临床应用分析  

Analysis of clinical use of the post-marketing Danhong injection based on hospital central monitoring method information system

作　　者：史琛[1] 赵瑛[1] 郑思维[1] 黄璞[1] 

机构地区：[1]华中科技大学同济医学院附属协和医院,湖北武汉430022

出　　处：《中国医院药学杂志》2014年第2期119-122,共4页Chinese Journal of Hospital Pharmacy

基　　金：国家科技支撑计划<中药上市后安全性监测与再评价标准规范的研究/中药注射剂重点监测和评价示范研究>子课题(编号:2006038086056)

摘　　要：目的:了解临床上应用丹红注射液的具体情况,为规范丹红注射液的临床应用提供参考。方法:采用集中监测法选取本院2010年3月-2012年2月使用丹红注射液的住院患者,从用药开始至用药结束15 d进行全程跟踪,填写评价筛选表,进行统计分析。结果:所有使用丹红注射液的住院患者中,54.69%的患者主要诊断或其他诊断符合丹红注射液说明书上的适应证;用药剂量超过说明书规定的范围的占8.2%;用药疗程过长或过短占10.35%和27.34%;选用溶媒不当的占13.67%;不良反应发生率为0。结论:丹红注射液不良反应的发生率较低,临床使用中药注射液欠规范,应加强管理。OBJECTIVE To study the state of Danhong injection used in clinical practice and to provide a reference ior gula- ing clinical use of Danhong injection. METHODS The whole process from start of the medication to the end, during 15 d was tracked by hospital central monitoring method. The data were filled in the screening table and the statistical analysis was per- formed. RESULTS In patients using Danhong injection, there were about 54. 69% percent patients who were prescribed based on main diagnosis,first visit and other diagnosis, which were also coincided with Danhong injection＇s instruction. In clinical practice,the dose more than the limits prescribed by the instructions accounted for 8. 2%; the drug treatment was too long or too short accounting for 10. 35% and 27.34% ; improper choice of solvent, accounting for 13.67% ; adverse events was 0. CONCLUSION The probability of adverse drug reaction occurred is low. Rational use of the TCM injection should be en- hanced.

关 键 词：丹红注射液 集中监测 临床应用 

分 类 号：R287[医药卫生—中药学]