原发性胆汁性肝硬化中医证治用药规律的文献研究  

Chinese Medicine Regularity on Primary Biliary Cirrhosis in Last Ten Years

作　　者：李红玉[1] 薛博瑜[1] 

机构地区：[1]南京中医药大学,南京210046

出　　处：《中国实验方剂学杂志》2014年第3期209-213,共5页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：国家科技重大专项项目(2008ZX10005-009)

摘　　要：目的:探索原发性胆汁性肝硬化的用药规律,以便于为该病的中医临床处方用药提供借鉴。方法:通过对文献的整理研究,将符合纳入标准和排除标准的原发性胆汁性肝硬化中医证治文献中的药物进行分类,用统计软件进行描述性统计。结果:治疗原发性胆汁性肝硬化使用频率较高的药物分别是茵陈(44%)、甘草(3.8%)、赤芍(3.8%)、茯苓(4.4%)、丹参(3.4%)、黄芪(3.4%)、当归(3.7%)、白术(3.9%),如果按归类则补虚药使用频率最高(27.3%),其次为活血化瘀药(17.0%)和利水渗湿药(16.1%)。结论:原发性胆汁性肝硬化用药有着自身的规律和特点,治疗原发性胆汁性肝硬化的过程中,在遵循中医辨证论治的前提下,应当重视对补虚药、活血化瘀药和利水渗湿药的使用。同时,一些已经被证实有利胆退黄作用的单味中药的加入,能更有效的治疗原发性胆汁性肝硬化这一病症。Objective： To explore the Chinese medicine for primary biliary cirrhosis＇s regularity and provide the prescription of clinical medicine for primary biliary cirrhosis. Method： Through arranging and researching, we classify the drugs in the literature of primary biliary cirrhosis and use statistical software to describe statistics. Result： The most frequently used Chinese medicine for the treatment of primary biliary cirrhosis are Ariemisiae Scopariae Herba, Glycyrrhizae Radix et Rhizoma, Paeoniae Radix Rubra, Poria, Salviae Miltiorrhizae Radix et Rhizoma, Astragali Radix, Angelicae Sinensis Radix, Atractylodis Macrocep halae Rhizoma. According to frequency of classified Chinese medicine Buxu drugs is the most frequently used, followed by Huoxue drugs and Lishi drugs. Conclusion： The Chinese medicine treat for primary biliary cirrhosis has its own laws and characteristics. In the treatment of primary biliary cirrhosis, attention should be payed to the using of Buxu drugs, Huoxue drugs and Lishi drugs. Meanwhile, joining some drugs which have been shown to have choleretic jaundice facts will have more effectire treatment for primary biliary cirrhosis.

关 键 词：原发性胆汁性肝硬化 中药 用药规律 文献研究 

分 类 号：R287[医药卫生—中药学]