婴儿隐孢子虫肠炎4例临床特点及九年后随访  

Clinical Features of 4 Cases of Infant Cryptosporidium Enteritis

作　　者：郑惠槟[1] 王瑛[1] 姚宜新[1] 

机构地区：[1]广州医学院附属市儿童医院,广州510120

出　　处：《广州医学院学报》2000年第4期44-46,共3页Academic Journal of Guangzhou Medical College

摘　　要：目的 :介绍隐孢子虫感染 4例婴儿肠炎的临床特点及 9年后随访的情况 ,探讨该病的有效防治措施。方法 :取患婴和家人以及所饲养的牲畜的新鲜粪便 ,用改良抗酸染色法涂片标本检查 ;并通过动物 (鼠 )模型的实验以确诊。结果 :在随机抽样的 2 71例 4岁以下腹泻婴幼儿住院者中 ,确诊 4例婴儿患隐孢子虫肠炎。检出率 1.4 7% (4/ 2 71)。经用大蒜素治愈出院。 9年后随访 ,患儿和其家人以及饲养牲畜之粪便检查 ,均呈阴性。结论 :隐孢子虫肠炎是人畜共患的寄生虫病 ,好发于夏季 ,多见于营养不良的小婴儿。患婴以腹泻为主 ,可伴发呼吸道疾患。大蒜素治疗效果显著 ,无副作用。婴儿感染与喂养方式 (母乳或人工 )相关性不明显 ,而与卫生环境、水源的污染密切相关。注意卫生和改善环境条件以及提高饮用、洗盥水的质量 。Objective:4 cases of infant Cryptosporidium entenitis were reported. Method: Fecal samples form 271 infants with diarrhea under 4 years old and their parents and the domestic animals were examined for cryptosporidium by the modified acid-fast staining. Animal models were used to confirmed the results. Result: 4 infants were diagnosed as cryptosporidium enteritis,with the positive rate of 1.47%. Diarrhea was the main clinical manifestation accompanied with respiratory disorders. The sick infants were cured by the use of garcilin. Fecal examinations were negative 9 years after the treatment. Conclusion: Cryptosporidium enteritis is a kind of zoonosis,mainly found in malnutritional infants. Garcilin is effective in the treatment of this disease.

关 键 词：隐孢子虫 隐孢子虫肠炎 临床特点 随访 婴儿 

分 类 号：R725.315[医药卫生—儿科]