贵州省黔南州1～14岁苗族儿童支气管哮喘病与生长发育的关系研究  

Study on the correlation between bronchial asthma and the growth and development of Miao children between the age of 1-14 in Qiannan Prefecture of Guizhou Province

作　　者：郭启燕[1] 杨予[2] 李溥[1] 宋发友 熊其江 李正福 韦艳萍 罗毅 班继超 

机构地区：[1]黔南民族医学高等专科学校 [2]贵州省惠水县人民医院 [3]贵州省瓮安县中医医院 [4]贵州省瓮安县人民医院 [5]贵州省罗甸县人民医院 [6]贵州省三都县人民医院 [7]贵州省福泉市第二人民医院 [8]贵州省长顺县人民医院

出　　处：《现代预防医学》2014年第2期222-224,共3页Modern Preventive Medicine

基　　金：贵州省高层次人才科研资助项目(TZJF2009073)

摘　　要：目的了解贵州省黔南州1．14岁苗族儿童支气管哮喘与生长发育指标的关系，为开展黔南地区儿童支气管哮喘的防治提供依据。方法选取2010年9月一2011年3月在黔南州12县（市）调查证实患哮喘病1～14岁苗族儿童260例为观察组。选择同期同年龄段正常儿童260名作为对照组，两组按年龄均分为4个年龄组，1—4岁、5—8岁、9．12岁和13。岁年龄组。分别测量两组各年龄段儿童身高、体重、胸围、BMI值及实验室检查血红蛋白（Hb）、碱性磷酸酶（AKP）及骨钙素（BGP）含量。观察组再根据患儿病情严重程度分为轻度哮喘病组、中度哮喘病组和重度哮喘病组3个亚组，组间进行比较。结果观察组各年龄段儿童身高、胸围、Hb、AKP及BGP含量水平分别与对照组比较，差异均有统计学意义（P〈O．01），而BMI指数值仅1～4岁年龄段与对照组比较，差异有统计学意义（尸〈0．05）。观察组重度哮喘儿童身高、体重、胸围、Hb、AKP及BGP含量水平分别与轻、中度哮喘病儿童比较，差异均有统计学意义（P〈0．01）。结论苗族哮喘儿童生长发育指标均低于同年龄段健康儿童，儿童哮喘病情越重，生长发育指标下降越明显。Objective The study aimed to determine the correlation between bronchial asthma and indicators of growth and develop- ment among Miao children aged between 1-14 years old in Qiannan Prefecture of Guizhou Province, hoping to provide references for the prevention and treatment of childhood bronchial asthma in the Qiannan area. Methods 260 Miao children between the age of 1-14 from 12 counties （or cities） in Qiannan Prefecture who had asthma and were confirmed by surveys conducted between September of 2010 and March of 2011 were selected as the observation group. 260 healthy children at the same age groups during the same period were selected as the control group. The two groups were equally divided into 4 age groups, including a 1-4 age group, a 5-8 age group, a 9-12 age group, and a 13- age group. Height, weight, chest circumference, body mass index （BMI）, and the levels of hemoglobin （Hb）, alkaline phosphatase （AKP）, and bone Gla-protein （BGP） of the two groups were measured. The ob- servation group was further divided into a mild asthma subgroup, a moderate asthma subgroup, and a severe asthma subgroup based on the severity of their conditions; and differences between the three subgroups were analyzed. Results Height, weight, and levels of Hb, AKP, and BGP of the observation group were compared with those of the control group, and the differences were statistically significant （P〈0.01）; however, only the BMI of the 1-4 age group were statistically different from that of the control group （P〈0.05）. Similarly, height, weight, chest circumference, and levels of Hb, AKP, and BGP of the children in the severe asthma subgroup were compared with those of the minor asthma and moderate asthma subgroups; the differences were also statistically significant （P〈0.01）. Conclusion Growth and development of the Miao children with asthma were poorer than that of healthy children at the same age group; that is, the more severe the asthma, the more significant retardation in growth and develop

关 键 词：支气管哮喘病 儿童 生长和发育 相互影响分析 

分 类 号：R562.25[医药卫生—呼吸系统]