机构地区:[1]湖北省妇幼保健院,武汉430070
出 处:《中国小儿急救医学》2014年第1期6-9,共4页Chinese Pediatric Emergency Medicine
基 金:湖北省公益性科技研究项目(2012DCA12005)
摘 要:目的对近4年来转运人院的新生儿中发生不良结局者的特点进行分析,为提高本省围生儿的生存质量及降低病死率提供参考。方法回顾性分析2008年1月至2011年12月问转运病例中发生不良结局者255例患儿的临床资料,并按时间先后分为A组124例(2008年1月至2009年12月)及B组131例(2010年1月至2011年12月),分析其基本资料、围生期因素及主要疾病等情况,并比较患儿在不同时期相关特点的变化。结果发生不良结局者中男性患儿比例明显高于女性(男:女为3.05:1,192:63),早产儿比例高(73.3%,187/255),剖宫产比例高(49.0%,125/255);主要疾病为呼吸系统疾病(71.4%,182/255),其次为循环系统疾病(40.4%,103/255)及严重先天发育异常(26.3%,67/255)。B组与A组比较:(1)住院时间〈24h者比例上升(73/131 vs 50/124,P〈0.05);(2)经过2次以上转院者增加(41/131 vs 23/124,P〈0.05);(3)极低出生体重儿(包括超低出生体重儿)显著增加(75/131 vs 43/124,P〈0.05);(4)呼吸系统疾病(131/131 vs 124/124)及窒息(9/131 vs 22/124)、缺氧缺血性脑病(6/131 vs 16/124)显著下降(P〈0.05);(5)循环系统疾病(60/131vs31/124)及先天发育异常者(51/131vs23/124)显著上升(P〈0.05);(6)机械通气(115/131vs88/124)及肺表面活性物质应用(85/131vs52/124)显著增加(P〈0.05);(7)血液制品使用率显著下降(39/131vs53/124,.P〈0.05);(8)因经济等原因放弃治疗者显著减少(22/131vs37/124,P〈0.05)。结论基层医疗机构对转运时机及转诊医院的选择,可能影响不良结局的发生率;高剖宫产率可能增加不良结局的发生;极低及超低出生体重儿的救治能力可能直接影响不良结局的发生;呼吸系统疾病�Objective To analyze the characteristics of newborns in occurrence of adverse outcomes that transferred from other hospitals during the past four years, in order to improve the province's perinatal survival quality and reduce mortality. Methods The clinical data of 255 cases in occurrence of adverse outcomes in transit during January 2008 to December 2011 were analyzed retrospectively. According chronologically 255 cases were divided into group A (124 cases, January 2008 to December 2009 ) and group B ( 131 cases,January 2010 to December 2011 ). We analyzed the basic data,perinatal factors and major diseases of the newborns,and compared the changes of related characteristics in different periods. Results Adverse out- comes in male patients were significantly higher than female patients ( male: female 3.05 : 1,192:63 ) ; there were higher proportion of premature infants (73.3 %, 187/255 ) and cesarean section (49%, 125/255 ). The major diseases were respiratory system diseases (71.4%, 182/255), followed by circulatory system diseases (40. 4%, 103/255), and severe congenital abnormalities (26. 3% ,67/255 ). Group B compared with group A: ( 1 ) the proportion of hospitalization time 〈 24 hours increased (73/131 vs 50/124, P 〈 0. 05 ) ; (2) the proportion of more than two referrals increased (41/131 vs 23/124, P 〈 0. 05 ) ; (3) the proportion of very low birth weight infants (including extremely low birth weight) increased significantly(75/131 vs 43/124, P 〈 0. 05 ) ; ( 4 ) the proportion of respiratory system diseased ( 131/131 vs 124/124 ), asphyxia ( 9/l 31 vs 22/124) and hypoxic ischemic encephalopathy ( 6/131 vs 16/124 ) decreased significantly ( P 〈 0. 05 ) ; (5) the proportion of circulation system diseased ( 60/131 vs 31/124 ) and congenital developmental abnormalities ( 51 / 131 vs 23/124) increased significantly ( P 〈 0. 05 ) ; (6) the application of mechanical ventilation ( 115/131 vs
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