单侧突聋患者对侧耳高刺激率ABR结果分析  

Analysis of Contralateral High-frequency Stimulation ABR in Patients with Unilateral Sudden Deafness

作　　者：程莉雅[1] 毕巍[2] 刘吉祥[2] 武斐[2] 邢轶卓[2] 

机构地区：[1]天津医科大学研究生院,天津300070 [2]天津市人民医院耳鼻喉头颈外科

出　　处：《听力学及言语疾病杂志》2014年第1期53-55,共3页Journal of Audiology and Speech Pathology

摘　　要：目的研究单侧突聋患者对侧耳高刺激率ABR的特点及临床应用价值。方法对40例（40耳）17～45岁单侧突聋患者（病例组）的健耳及同龄听力正常人20例（40耳，对照组）双耳分别进行纯音测听和高（55．1次／秒）、低（11．1次／秒）刺激率听性脑干反应（ABR）检测，以两种刺激率下ABRⅠ-Ⅴ波间期（interpeaklatency，IPL）差值（△IPL）〉0．28为异常，比较两组检测结果及Ⅰ—Ⅴ△IPL异常率。结果①病例组健耳和对照组各频率纯音听阈无统计学差异；②病例组健耳高刺激率ABR波Ⅰ潜伏期比对照组明显延长（P〈0．001），其余各波潜伏期、波间期及波Ⅴ反应阈均无统计学差异；③病例组健耳Ⅰ-Ⅴ波间期差值异常率为62．5％（25／40），对照组为50（2／40），病例组高于对照组（X^2=29．574，P〈0．001）。结论单侧突聋患者健耳高刺激率ABR波Ⅰ潜伏期明显延长，高、低刺激率ABRⅠ-Ⅴ波间期差异常率明显增加，提示单侧突聋患者对侧耳可能同时存在内耳血供异常。Objective To analyze the characteristic and the clinical application of high-frequency stimulation ABR for the patients with unilateral sudden deafness. Methods 40 patients aged 17-45 with unilateral sudden deaf-ness（40 health ears , subject group）and 20 normal volunteers （40 ears , control group）were selected to receive high and low frequency stimulation ABRs and pure tone audioraetry. Results There were no statistical differences be-tween subject group and control group in pure tone audiometry. The wave Ⅰ latency of high-frequency ABR was longer in the subject group than that in the control group（P（0. 001）. The abnormal rate ofⅠ -Ⅴ interval between high and low frequency stimulation ABRs was 62.5%（25/40） in the subject group ,and 5%（2/40） in the control group . There were statistical differences between the two groups （X^2 = 29. 574, P〈0. 001）. Conclusion The wave Ⅰ latency of high-frequency ABR was longer and the abnormal rate of Ⅰ - Ⅴ interval markedly increased in the health ear of patients with unilateral sudden deafness. This may suggest that the contralateral ear may have an ab- normal blood supply of the inner ear when single side sudden deafness happened. High frequency stimulation ABR can be used to detect the potential changes of contralateral ear before the hearing loss occurred.

关 键 词：突发性聋 听性脑干反应 刺激率 

分 类 号：R764.04[医药卫生—耳鼻咽喉科]