应用GQI技术对小脑髓质的初步研究  

The preliminary study of the cerebellum medulla using Generalized Q-sampling Imaging

作　　者：陈一勇[1] 尹维刚[1] 林荣[1] 王守道[1] 汪海清[1] 李林[2] 

机构地区：[1]宁波大学医学院,浙江宁波315211 [2]南京医科大学解剖教研室,南京210029

出　　处：《中国临床解剖学杂志》2014年第1期36-40,共5页Chinese Journal of Clinical Anatomy

摘　　要：目的应用基于GQI的弥散成像方法,对小脑的纤维束进行重建和显示,为小脑疾病的影像诊断进行解剖学和技术上的探索。方法首先把10例脑连接组项目的磁共振弥散数据导入DSI-studio软件,然后依次用该软件中的GQI(Generalized Q-sampling imaging)成像技术和流线算法(streamline algorithm)对与小脑有关的纤维束进行重建和显示。结果 (1)在DSI-studio软件的二维和三维界面中显示了小脑三对脚的位置和交叉情况;(2)显示了小脑3对脚与脊髓、延髓、脑桥、中脑、端脑等的连接情况及其主要纤维成分。结论应用GQI技术可以对小脑白质进行重建和显示,为小脑疾病的影像学诊断提供技术和结构学上的帮助。Objective To show the fibers that connected the cerebellum with brainstem, diencephalon and spinal cord using GQI. Methods We acquired high-resolution structural and diffusion MRI of 10subjects from HCP. The 4tractography based on a GQI and streamline algorithm of the DSI-studio software was performed to reconstruct and show the fibers that linked the cerebellum with other parts of the CNS（Central Nervous System）. Results （1） 2-dimensional and 3-dimensional positions and intersections of the superior （SCP）, and middle （MCP） and inferior （ICP） cerebellar peduncles were showed using the DSI- studio software. （2） the main ingredients of the three peduncles of cerebellum which connected to the spinal cord, medulla oblongata, pons, midbrain, diencephalon were 3-dimensionally demonstrated. Conclusions The cerebellum medulla can reconstructed and displayed using GQI, providing a diagnostic tool for characterizing anatomical disruptions that occur in cerebellar diseases and for monitoring response to therapeutic interventions.

关 键 词：GQI 脑连接组项目 DSI-studio软件 小脑髓质 

分 类 号：R323[医药卫生—人体解剖和组织胚胎学]