轻度子宫内膜异位症患者供精人工授精治疗方案的比较  

Therapeutic Regimen Comparison of Artificial Insemination by Donor on Mild Endometriosis

作　　者：刘宇 付艳霞[2] 陈瑞玲 陆艳华 宋革 钟小英 姜荣华 郑炜炜 李秋华 

机构地区：[1]广东省计划生育专科医院,广东广州510060 [2]中山大学附属第一医院,广东广州510080

出　　处：《实用妇产科杂志》2014年第1期29-32,共4页Journal of Practical Obstetrics and Gynecology

基　　金：广东省人口计生委科技项目(编号:2010206)

摘　　要：目的:探讨轻度子宫内膜异位症患者在腹腔镜诊治术后2年内,自然周期和促排卵周期供精人工授精(AID)的妊娠结局。方法:回顾性分析303周期(168例)无排卵障碍的轻度子宫内膜异位症患者AID情况,比较在腹腔镜诊治术后2年内,自然周期(78例,195周期)与促排卵周期(90例,108周期)AID助孕后的周期妊娠率;同时比较在促排卵周期中,单卵泡排卵与多卵泡排卵的周期妊娠率。结果:在所有研究患者中,妊娠47例,其中自然周期妊娠率为16.9%(33/195),促排卵周期妊娠率为13.0%(14/108),二者比较差异无统计学意义(P=0.362)。在促排卵周期中,单卵泡排卵周期妊娠率13.5%(7/52),多卵泡排卵周期妊娠率12.5%(7/56),二者比较差异无统计学意义(P=0.882)。结论:对于排卵正常的轻度子宫内膜异位症患者,在助孕方式的选择中,可以优先选择自然周期人工授精。Objective：To investigate the pregnant outcomes of mild endometriosis patients treated by the natural cycle or the induction ovulation cycle pregnancy for artificial insemination by donor（AID）with laparo- scopic treatment within 2 years. Methods ：303 cycles（168 cases）of AID of mild endometriosis patients with- out ovulation disorders which had the laparoscopic treatment within two years were retrospectively analyzed. The pregnancy rate in the natural cycle group and the induction ovulation cycle group was compared. The pregnancy rate in single follicle ovulation and multi-follicular ovulation cycle in the induction ovulation cycle group was compared. Results：In all patients in the study,47 of the all patients got pregancies,including 33 in the natural cycle group（ 16.9% ,33/195 ）and 14 in the induction ovulation cycle group（ 13.0%, 14/108 ）. The difference between two groups was not statistically significant（ P = 0. 362）. The pregnancy rate of single folli- cle ovulation cycle and multi-follicular ovulation cycle （ the number of follicles ~〈 3） was 13.5% （7/52） and 12.5% （7/56）, respectively in induction ovulation cys. The difference was not statistically significant（ P = 0. 882）. Conclusions：The natural cycle of artificial insemination should be a better choice to the mild endo- metriosis patients with normal ovulation.

关 键 词：子宫内膜异位症 供精人工授精 周期妊娠率 自然周期 促排卵周期 

分 类 号：R711.71[医药卫生—妇产科学]