卵巢早衰的研究现状与进展  

Premature Ovarian Failure: Current Outlook

作　　者：赵倩[1] 叶宸[1] 李文[1] 

机构地区：[1]第二军医大学长征医院生殖医学中心,上海200003

出　　处：《生殖与避孕》2014年第1期59-64,共6页Reproduction and Contraception

基　　金：上海市科委国际合作项目;项目号:11410708400

摘　　要：卵巢早衰(POF)是生殖医学的一大难题,卵子形成与发育的任一环节受损都有可能导致POF。POF的病因复杂多样,其中遗传因素目前认为是最主要的原因,而环境因素近几年越来越受到重视。能被病因诊断的POF患者极少,大量研究专注于寻找POF形成的相关基因。改善低雌激素引起的症状,尽可能恢复患者生育功能是POF的主要治疗原则。Premature ovarian failure （POF） is a grand challenge in reproductive endocrinology. The disruption in the course of follicle formation and development would lead to POF. The etiology of POF is multiple and complex. Genetic factor is thought to be the main reason for POF by now and the environmental factor is more and more concerned recently. Only a few patients of POF could be etiological diagnosed. A large quantity of researches have been designed to explore the relative genes of POF. Improving the symptoms with low estrogen and recovering the fertility as far as possible are the main treatment for POF.

关 键 词：卵巢早衰(POF) 病理生理 病因 诊断 治疗 

分 类 号：R711.75[医药卫生—妇产科学]