血清同型半胱氨酸检测诊断冠心病的临床意义  

作　　者：马涛[1] 陈峻[1] 张惜[1] 

机构地区：[1]武汉市第一医院检验科,湖北武汉430022

出　　处：《中医学报》2013年第B12期249-249,共1页Acta Chinese Medicine

摘　　要：目的：为探讨血清同型半胱氨酸（Hcy）的检测在冠心痛预防，诊断及治疗上的临床价值。方法：采用日本OLMPUS公司AU2700全自动生化分析仪检测150例冠心痛患者及100例健康对照者血清Hcy水平，并进行比较。结果：冠心痛组血清Hcy明显高于健康对照组（P〈0．05）。冠心病组高同型半胱氨酸血症的发生率60％（90例）明显高于健康对照组的4％（4例）（P〈0．05）。另外陈旧性心肌梗死组，不稳定性心绞痛（UAP）组，稳定性心绞痛（SAP）组三组之间Hcy水平比较，从高到底依次为陈旧性心肌梗死组，不稳定性心绞痛组，稳定性心绞痛组，差异有统计学意义（P〈0．05）。结论：Hcy是评价冠心病的独立危险因素，且Hey水平随着冠心病程度的加重而增加，检测Hcy对冠心病的预防，诊断，治疗和预后判断具有重要的临床意义。Objective to explore serum homocysteine （Hcy）detection in coronary heart disease prevention,diagnosis and treatment of clinical value. Meth- ods using Japan OLMPUS company AU2700 automatic biochemical analyzer test 150 cases of coronary heart disease patients and 100 cases of healthy controls serum Hcy levels, and compare. Results serum Hcy in coronary heart disease （CHD）group was obviously higher than that of the health control group （P 〈0.05）. Coronary heart disease group of hyperhomoeysteinemia appear to be the incidence rate of 60% （90cases）was obviously higher than that of the health control group 4% （4cases）（P〈0. 05）. In addition to old myocardial infarction group, unstable angina pectoris（UAP）gronp, stable angina pectoris（SAP） group of three groups of Hcy levels between comparison, from high to low in the old myocardial infarction group, unstable angina pectoris group, stable angina pectoris group,the difference was statistically significant （P 〈 0.05）. Conclusion Hcy is to evaluate independent risk factors of coronary heart disease, and Hcy levels with coronary heart disease degree of increase and increase, Hcy detection of coronary heart disease prevention,diagnosis, treatment and prognosis judge has important clinical significance.

关 键 词：冠心痛 同型半胱氨酸 高同型半胱氨酸血症 

分 类 号：R696.4[医药卫生—泌尿科学]