61例交叉配血不相合原因分析  

Analysis and management of 61 cases of incompatible cross-matching

作　　者：樊凤艳[1] 祁术元[1] 熊梅[1] 魏少平[1] 周菁[1] 刘娟[1] 王洪波[1] 

机构地区：[1]空军总医院输血科,北京100142

出　　处：《空军医学杂志》2013年第3期152-154,共3页Medical Journal of Air Force

摘　　要：目的探讨各种原因导致配血不相合的解决办法。方法对我院的61例交叉配血不相合的26例标本进行血型鉴定、意外抗体鉴定、献血者标本检测等免疫血清学分析,查找不相合原因,针对配血不相合原因进行不同方法的交叉配血,并对各种交叉配血不相合原因及同种抗体鉴定结果进行统计分析。结果多种原因可导致交叉配血结果不相合,其中人为因素(操作失误)11例,血型鉴定困难11例,献血者原因17例,患者同种抗体17例,自身抗体5例。抗-E在同种抗体中的比例为12/17。61例交叉配血不相合患者标本经过正确处理后均找到了相合的血液输注,均未发生输血反应。结论交叉配血不相合时应在保证消除人为因素(操作失误)的前提下综合分析原因,并选用相适应方法进行交叉配血,才能保障临床输血安全有效。Objective To explore measures for incompatible cross-matching by analyzing 61 cases of incompatible cross-matching. Methods Samples with incompatible cross-matching in recent 2 years in our hospital were tested with blood grouping, unexpected antibody identification and serological tests of store blood. Tests of cross-matching based causes of inconformity of cross-matching were performed. Whether there was significant difference between ratio of anti-E in our test and reported 22/37 was analyzed. Results Several causes were found can induce inconformity of cross-matching. The amount of causes of incompatible cross-matching found among 61 cases were： artificial causation 11, unconformity of forward and reverse ABO blood grouping 11, disqualification of store blood 17, allo-antibody 17, auto-antibody 5. There was no significant difference between ratio of anti-E in our test and reported 12/17. No blood transfusion reactions were observed among 61 cases after compatible stored blood transfusion. Conclusion Analysis and management of causes for inconformity of cross-matching can ensure compatibility of stored blood and transfusion safety.

关 键 词：交叉配血 不相合 

分 类 号：R457.1[医药卫生—治疗学]