正交试验法优选复方当益颗粒成型工艺  

Optimization of Forming Technology for Compound Dangyi Granules by Orthogonal Experiments

作　　者：龙翊婷[1] 蒋伟哲[1] 黄增琼[1] 巫玲玲[1] 王绍龙[1] 朱海瑛[1] 

机构地区：[1]广西医科大学,广西南宁530021

出　　处：《中国药业》2014年第2期52-53,共2页China Pharmaceuticals

摘　　要：目的优选复方当益颗粒的最佳成型工艺。方法以颗粒的成型性、溶解性、吸湿性和流动性为考察指标,用L9(34)正交试验优选成型工艺。结果最佳成型工艺为采用糊精作为稀释剂,水为润湿剂,混合粉末与润湿剂用量比为10∶4.5。结论该工艺合理可行,稳定可靠,可为生产提供依据。Objective To optimize the optimum forming technology for Compound Dangyi Granules. Methods The forming technology of Compound Dangyi Granules was optimized by Z^（34） orthogonal experiments with the formability,solubility,hygroscopicity and liquidity of granules as the indexes. Results The optimum forming technology were as follows ： dextrin was used as the diluent, water used as the wetting agent, the ratio of mixed powder to the wetting agent was 10：4. 5. Conclusion This forming technology is reasonable, feasible, stable and reliable,which can provide a basis for production.

关 键 词：复方当益颗粒 成型工艺 正交试验 

分 类 号：TQ461[化学工程—制药化工] R284.1[医药卫生—中药学]