氟硼荧染料修饰衍生研究进展  

Research progress of functional modification of boron dipyrromethene(BODIPY)fluoresecent dyes

作　　者：于长江[1] 焦莉娟[1] 郝二红[1] 

机构地区：[1]安徽师范大学化学与材料科学学院,安徽芜湖241000

出　　处：《中国科技论文》2013年第12期1291-1297,共7页China Sciencepaper

基　　金：高等学校博士学科点专项科研基金资助项目(20093424120001);安徽师范大学科研培育基金资助项目(160-721246)

摘　　要：氟硼荧光(BODIPY)染料是近些年来新兴起来的,与传统染料相比大多都具有优异光化学物理性能的一类荧光化合物。尤其是长波近红外的BODIPY荧光染料,更适合于活体细胞成像进而研究生命过程的发生和变化。然而其吸收和发射波长都处于小于600nm的可见区域。因此,研究BODIPY荧光染料的合成方法以及通过对其进行修饰衍生实现吸收发射光谱红移尤为必要。笔者总结了目前常见的BODIPY荧光染料分子的合成方法及其修饰衍生方法,并对这些方法优缺点进行了比较。Abstract： Boron dipyrromethene （BODIPY） dye as a kind of fluorescent dye has been developed in recent years, which has out- standing physicochemical properties, especially for long wavelength and near-IR BODIPY dyes. However, the , and aem of BODIPY are less than 600 nm, which makes it very necessary to research synthetic methods and functional modification in order to realize spectral redshift. In this paper, synthetic methods and functional modification of BODIPY fluorescent dyes are re- viewed, and the advantages and disadvantages of these methods are easily discussed.

关 键 词：荧光染料 氟硼二吡咯 合成方法 修饰 

分 类 号：TQ617.3[化学工程—精细化工]