维持性血液透析患者感染的临床特点及相关因素分析  

Analysis of clinical characteristics and related risk factors of maintenance hemodialysis in patients with infection

作　　者：贾丽芳[1] 冯悦民[1] 王甲正[1] 

机构地区：[1]首都医科大学大兴医院肾内科,北京102600

出　　处：《山西医科大学学报》2014年第1期47-49,共3页Journal of Shanxi Medical University

摘　　要：目的分析维持性血液透析（MHD）住院患者感染的发生情况及相关因素。方法对大兴区人民医院2011-01-2013-06收治的97例次维持性血液透析患者住院病例进行回顾性分析，根据是否发生感染分为感染组和非感染组，比较两组患者的年龄、透析龄、血红蛋白、C反应蛋白（CRP）、透析前尿素氮、血肌酐、血浆白蛋白、尿素清除指数（KT／V）等临床指标，分析维持性血液透析患者感染发生情况及临床特点。结果97例次MHD住院中因感染性疾病住院38例，感染率为39．2％，其中最常见感染为肺部感染23例，占因感染住院的60．5％，其次为深静脉导管感染6例，占15．8％。感染组年龄、CRP高于非感染组[（65．16±7．68）岁郴（58．95±9．00）岁，（44．05±14．11）哪（10．12±4．34）g／L，P〈0．01]，血红蛋白和血浆白蛋白水平低于非感染组[（91．86±10．92）g/Lvs（102．14±4．96）g/L；（27．97±2．48）g／Lvs（34．58±1．87）g／L，P〈0．01]。结论维持性血液透析患者感染以肺部感染多见，感染者多存在年龄大、CRP高、贫血、低蛋白血症等临床特点。Objective To analyze the incidence of infection and its clinical characteristics in the maintenance hemodialysis （MHD） patients. Methods A total of 97 hospitalized MHD cases were enrolled in this study. Age, dialysis duration,hemoglobin, serum creat- inine,plasma albumin,CRP and KT/V were compared between infection group and non-infection group. Results Of 97 cases,38 ca- ses（39.2% ） were hospitalized because of infection, including the pulmonary infection（ 60.5%, 23/38 ）, followed by central venous catheter infection 15.8% （6/38）. Patients were older in infection group than in non-infection group[ （65.16 ±7.68） vs （58.95±9.00） years, P 〈 0.01 ]. The levels of CRP were higher in infection group than in non-infection group [ （44.05 ±14.11 ） vs （10.12±4. 34）g/L,P 〈0. 01 ]. The levels of hemoglobin and serum albumin were lower in infection group than in non-infection group [ （91.86 ± 10.92） vs （102.14±4.96）g/L,（27.97±2.48） vs （34.58±1.87）g/L,P〈0.01]. Conclusion The most common infection is the pulmonary infection in MHD patients. Infection cases are older and have higher CRP and lower hemoglobin and plasma albumin.

关 键 词：血液透析 感染 相关因素 

分 类 号：R692.5[医药卫生—泌尿科学]