常规疗法与布地奈德雾化吸入法治疗小儿肺炎的疗效对比分析  

Analysis of efficacy of budesonide inhalation in the treatment of children with pneumonia

作　　者：邓春晖[1] 姚毅[1] 

机构地区：[1]达州市中心医院儿科,四川达州635000

出　　处：《临床肺科杂志》2014年第2期298-300,共3页Journal of Clinical Pulmonary Medicine

摘　　要：目的比较常规疗法与布地奈德雾化吸入法治疗小儿肺炎的疗效。方法将100例小儿肺炎患者随机均分为对照组与观察组,分别给予常规疗法与布地奈德雾化吸入法治疗。结果观察组IL-18水平明显高于对照组,观察组TNF-α、TGF-β1均明显低于对照组,且两组上述指标差异均具有统计学意义(P<0.05,P<0.01);观察组体温恢复时间、咳嗽消失时间及肺部啰音消失时间均明显低于对照组(P<0.05);两组治疗过程中均未出现不良反应。结论布地奈德雾化吸入法治疗小儿肺炎的疗效显著,值得在临床应用。Objective To compare the curative effect between conventional therapy and budesonide inhala- tion in the treatment of children with pneumonia. Methods 100 children with pneumonia were randomly divided into the control group and the observation group, who were respectively treated with conventional therapy and budesonide inhalation. The levels of IL-18, TNF-α and TGF-β1 levels were recorded before and after the treatment. Their clini- cal symptoms and incidence of adverse reactions were compared between the two groups. Results The level of IL-18 was significantly higher in the observation group than in the control group （ P 〈 0. 05 ）, and the levels of TNF-α and TGF-β1 were lowe in the observation group than in the control group （P 〈 0. 01 ）. The improvement of temperature recovery, cough and pulmonary rales was more pronounced in the observation group than in the control group （ P 〈 0. 05）. There was no obvious adverse reactions occurred in the two groups. Conclusion Budesonide inhalation has significantly curative effect in the treatment of children with pneumonia.

关 键 词：常规疗法 布地奈德雾化吸入法 小儿肺炎 疗效 

分 类 号：R725.6[医药卫生—儿科]