蒙脱石及其复合物作为药物载体的研究进展  

Research Progress of Montmorillonite and Its Composites as a Drug Carrier

作　　者：陈灵芝[1] 孔令钰[2] 王倩[2] 

机构地区：[1]天津中医药大学,天津300193 [2]天津市医药科学研究所,天津300020

出　　处：《天津科技》2014年第1期5-8,共4页Tianjin Science & Technology

基　　金：天津市卫生局科技基金资助项目(2012KY33)

摘　　要：在医药领域,蒙脱石具有多种优良药用辅料性能,开发潜力巨大。对蒙脱石作为药物载体的研究呈逐年增加的趋势,主要是对蒙脱石作为抗肿瘤药的缓、控释制剂载体的研究,近年来亦有对其作为矫味和降低毒副作用载体的研究。分两大类概括总结了蒙脱石作为药物载体的国内外最新研究进展,为今后科研工作者做蒙脱石给药系统的深入研究提供了科学依据。Montmorillonite （MMT） is known for its wide application as a pharmaceutic adjuvant and its huge market potential in the field of pharmaceutical sciences. In recent years, MMT as a drug carrier has attracted growing interests from researchers and most of the efforts were put into MMT as a carrier of sustained or controlled release preparations for antineoplastic drugs. Some also focused on its role as a carrier for correctives and a carrier to reduce toxic and side effects. From a perspective of two categories, a summarization of recent research progresses of MMT and its composites as a drug carrier both in China and other countries and areas was made, aiming to provide scientific proofs for any researcher who wishes to carry out in-depth study in MMT-based drug delivery system.

关 键 词：蒙脱石 载体 缓释 控释 

分 类 号：R917[医药卫生—药物分析学]