右美托咪定与拉贝洛尔在治疗颈丛神经阻滞颈部手术中不良心血管反应的临床比较  

Clinical comparison of adverse cardiovascular reactions treated by dexmedetomidine and labetalol under cervical plexus nerve block and neck surgery

作　　者：鲁小民[1] 巫水生[2] 陈杏媛[3] 刘贤琼[1] 王遂之[1] 戴玉[2] 

机构地区：[1]江西省吉安市中心人民医院麻醉科,江西吉安343000 [2]江西省吉安市中心人民医院急诊科,江西吉安343000 [3]江西省吉安市中心人民医院检验科,江西吉安343000

出　　处：《中国当代医药》2014年第2期115-116,122,共3页China Modern Medicine

摘　　要：目的观察右美托咪定与拉贝洛尔在治疗颈丛神经阻滞颈部手术中不良心血管反应的效果差异。方法选择2009年5月～2013年5月本院采用颈丛神经阻滞麻醉行颈部手术患者100例，随机分成右美托咪定组（D组）和拉贝洛尔组（L组），每组各50例。D组患者在颈丛神经阻滞后辅助应用右美托咪定，维持血流动力学；L组在颈丛神经阻滞后辅助应用拉贝洛尔。观察两组患者并发症的发生情况。结果D组的并发症发生率（14．0％）显著低于L组（34．O％）（P〈0．05）。D组能很好地维持术中血流动力学稳定，且患者感觉舒适，能很好地耐受手术体位；L组血流动力学有所波动，且患者难以耐受手术体位，需加用镇静剂才可完成手术。结论在颈丛神经阻滞下行颈部手术时，使用右美托咪定能很好地维持术中血流动力学稳定，且患者能很好地耐受手术体位。Objective To observe the effect difference of dexmedetomidine and labetalol in the treatment of adverse cardiovascular reactions under cervical plexus nerve block and neck surgery. Methods 100 patients who were under- went cervical plexus nerve block and neck surgery from May 2009 to May 2013 were selected,and they were randomly evenly divided into dexmedetomidine group（D group） and labetalol group（L group）.Patients in D group and L group were provided with dexmedetomidine and labetalol respectively to maintain hemodynanfics after cervical plexus blockage.The occurrence of complications in both groups were observed. Results The incidence of complications in D group was 14.0%, which was lower than that of L group（34.0%）（P〈0.05）.In D group,the hemodynamics was stably maintained,and the patients felt comfortable and the surgical positions were acceptable.However, in L group,the hemodynamics was fluctuated,and the patients couldn＇t bear the surgical positions,the surgery was finished only after added tranquilizer. Conclusion For neck surgery through cervical plexus blockage,dexmedetomidine can maintains the stability of hemodynamics during surgery and patients can stand the surgical positions.

关 键 词：右美托咪定 拉贝洛尔 颈丛神经阻滞 颈部手术 

分 类 号：R971.2[医药卫生—药品]