COPD中医病位证素分布规律及其与病程、年龄的相关性研究  

Research on TCM Syndrome Elements of Disease Location Distribution Rules and the Correlation between TCM Syndrome Elements of Disease Location and Duration of the Disease and Age in Patients with COPD

作　　者：柯庚申[1] 洪敏俐[2] 李灿东[1] 洪春霖[2] 杨朝阳[1] 刘燕鸿[2] 黄小华[2] 高凌云[2] 

机构地区：[1]福建中医药大学,福建福州350108 [2]福建中医药大学附属漳州中医院,福建漳州363000

出　　处：《中医学报》2014年第2期186-188,共3页Acta Chinese Medicine

基　　金：福建省卫生厅青年科研课题(编号:2010-1-47);陈可冀中西医结合发展基金资助项目(编号:CKJ2010004);福建省中医肺系病重点研究室建设项目(编号:2013-内科类5)

摘　　要：目的:探讨慢性阻塞性肺疾病(COPD)稳定期患者中医病位证素分布规律及其与病程、年龄的相关性。方法:选择COPD稳定期患者151例,采用证素辨证和积分的方法,提取病位证素,对其进行统计分析,探讨COPD稳定期患者中医病位证素分布规律,以及随病程延长和年龄增长病位证素的演变规律。结果:常见病位证素有9个,主要病位证素有肺、肾,其次是心、脾。随着病程延长,肺病位构成比逐渐减少,而肾病位构成比逐渐增加。肺、肾、心病位积分随病程延长而增加。脾、肾病位积分随年龄增长而增加。结论:COPD稳定期病位主要在肺、肾,但亦累及心、脾等其他脏腑;COPD随着病程的延长而由肺及肾进行演变的,且其病理损害随着病程的延长而逐渐加重;而病位证素脾和肾的病理损害随年龄的增长而加重。Objective ：To investigate Traditional Chinese Medicine （TCM） syndrome elements of disease location distribution rules and correlated its with duration of the disease and age in patients with chronic obstructive pulmonary disease （COPD） at stable phase. Methods：A total of 151 patients with stable COPD were enrolled. TCM syndrome elements of disease location were extracted by syn- drome elements differentiation and integral methods. TCM syndrome elements of disease location distribution characteristics were ex- plored using statistical analysis in patients with stable COPD. The evolvement rule of syndrome elements of disease location were investi- gated with the extension of duration of the disease and age growing up. Results ：There were nine common syndrome elements of disease location, and main syndrome elements of disease location were the lung, the kidney, followed by the heart and the spleen. With the dura- tion of the disease extension, the constituent ratio of syndrome element of lung dropped off while the constituent ratio of syndrome ele- ment of kidney increased gradually. The scores of the lung, the kidney, the heart increased respectively with the duration of disease ex- tension. The integrals of the spleen and the kidney tended to increase with age. Conclusion ： The main syndrome elements of disease loca- tion are the lung and the kidney, but also affect the heart, the spleen, and the other viscera in patients with COPD. With the extension of duration of the disease, syndrome element of disease location evolved from lung to kidney, and its pathologic damage were more serious with extension of duration of the disease. Meanwhile pathologic damage of syndrome elements of spleen and kidney aggravated with the age.

关 键 词：慢性阻塞性肺疾病 病位 证素 病程 年龄 

分 类 号：R259.63[医药卫生—中西医结合]