新洁尔灭对比乙醇用于青霉素皮试消毒效果的Meta分析  

Bromogeramine vs ethanol for disinfection of penicillin skin test： A Meta- analysis

作　　者：赵凤娥[1] 关秀琼[1] 吴兰英[1] 

机构地区：[1]南方医科大学附属新会医院手足外科,江门529100

出　　处：《中国实用护理杂志》2014年第2期55-58,共4页Chinese Journal of Practical Nursing

摘　　要：目的评价新洁尔灭对比乙醇消毒对于青霉素皮试效果的影响。方法检索CNKI、维普、万方学位论文全文数据库、中国生物医学文献数据库平台从建库到2013年5月的文献，对符合纳入标准的文献进行质量评价并提取数据。采用RevMan5．0．0软件进行Meta分析。结果最终纳入4篇文献，共计1954人。Meta分析显示结果如下：经敏感性分析去除异质性后，新洁尔灭和乙醇消毒用于青霉素皮试的阳性结果存在统计学差异[Z=2．15，P=0．03，合并OR值为0．70（95％GI．50,-,0．97）]；经敏感性分析去除异质性后，新洁尔灭和乙醇消毒用于青霉素皮试的假阳性率存在临界统计学差异[Z=1．89，P=0．06，合并OR值为0．55（95％CI=0．29～1．02）]。结论新洁尔灭用于青霉素皮试消毒时，阳性结果和假阳性率较低。表明对于青霉素皮试消毒，新洁尔灭优于乙醇。Objective To evaluate the bromogeramine and ethanol for effects of disinfecting in peni- cillin skin test. Methods Searching CNKI, VIP, CBM and Wanfang Database to collect case-control studies suiting enrolled conditions. Meta-analysis was conducted by RevMan 5.0.0 software. Results Four case-con- trol studies with 1 954 people were enrolled. After exclude one study using sensitivity analysis, Meta analy- sis showed： there were significant differences between positive results of bromogeramine and ethanol, Z= 2.15, P=- 0.03, OR= 0.70, 95%CI=0.50-0.97. There were significant differences between false positive rates of bromogeramine and ethanol, OR=0.55, 95%CI=0.29-1.02. Conclusions Comparing with ethanol, bro- mogeranine has lower positive results and false positive rate, which suggests that bromogeramine may be better than ethanol in penicillin skin test disinfection.

关 键 词：新洁尔灭 青霉素 皮试 皮内注射 META分析 

分 类 号：R187[医药卫生—流行病学]