CsOH/DMSO促进下卤代芳烃与酚的反应:一种合成二芳基醚的简便方法  

CsOH/DMSO Promoted Reactions of Aryl Halides with Phenols: A Convenient Method for the Synthesis of Diaryl Ethers

作　　者：陈平良[1] 陆世杰[1] 胡新根[1] 徐清[1] 

机构地区：[1]温州大学化学与材料工程学院,温州325035

出　　处：《有机化学》2014年第1期112-117,共6页Chinese Journal of Organic Chemistry

基　　金：国家自然科学基金(Nos.21073132;20902070)资助项目~~

摘　　要：在氢氧化铯/二甲基亚砜(CsOH/DMSO)碱体系促进下,卤代芳烃与酚可在加热条件下直接反应,生成二芳基醚.该反应无需使用过渡金属催化剂和配体,亦无需惰性气体保护,是一种简洁的绿色合成方法.基于一系列实验结果,我们提出了经由苯炔进行的反应机理.The reactions of aryl halides with phenols promoted by CsOH/dimethyl sulfoxide （CsOH/DMSO） led to diaryl ethers. This method was free of transition metal catalysts and ligands, and could be performed without inert gas protection. Therefore, it was a concise and green synthetic method. Based on the experimental results, a mechanism involving the benzyne intermediates is supposed.

关 键 词：卤代芳烃 酚 二芳基醚 氢氧化铯 二甲基亚砜(DMSO) 苯炔 

分 类 号：O625.322[理学—有机化学]