牵引疗法在Peyronie病治疗中的应用现状及展望  

Application of traction therapy for Peyronie's disease:Present and prospect

作　　者：何宗海[1] 卢一平[1] 

机构地区：[1]四川大学华西医院泌尿外科,四川成都610041

出　　处：《中华男科学杂志》2014年第1期78-82,共5页National Journal of Andrology

摘　　要：阴茎硬结症又称Peyronie病，是一种以阴茎海绵体白膜纤维性结节、斑块形成为特征的良性慢性病变，发病年龄多见于45—60岁。Peyronie病的确切病因尚不清楚，其病理生理表现为纤维蛋白和胶原蛋白的局部沉积。临床表现为阴茎硬结、痛性勃起和（或）勃起时阴茎弯曲畸形，常伴有心理障碍和（或）勃起功能障碍（ED）。Peyronie病的治疗策略可分为保守治疗、手术治疗以及综合治疗。不同的治疗策略适应症各异，各有其优缺点，但现有Peyronie病治疗方法的总体疗效不佳，目前也无单一的标准治疗方法可供选择。近几年，国外有关将牵引疗法用于治疗Peyronie病的报道逐渐增多。在治疗Peyronie病时，牵引疗法可以单独或者与其他治疗方法联合使用，并且可以在手术治疗前后应用。现有的研究结果显示：牵引疗法在阻止Peyronie病的瘢痕进展，恢复阴茎长度及周径，减少阴茎弯曲，改善性功能等方面显示出优势。但是，由于现有的报道多缺乏统计学设计，因此，需要大样本、多中心、随机对照研究进一步证实牵引疗法的有效性。另外，应该加大对Peyronie病发病机制的研究力度，争取从根本上防治Peyronie病。Peyronie＇s disease is an acquired connective tissue disorder affecting the tunica albuginea of the corpus cavernosum, causing penile plaque formation and persistent scar. It typically affects males between the ages of 45 and 60 years. The exact cause of Peyronie＇s disease is not clear and its pathological and physiological performance is the local deposition of fibrin and collagen. Men afflicted by this disorder may present with erectile pain, penile deformity （such as penile curvature or penile shortening）, psychological disorder and/or erectile dysfunction. Though many medical and surgical options have been developed for the treatment of Peyronie＇s disease and each has its own indications, advantages and disadvantages, none of them produces very desirable effect. The studies of traction therapy for Peyronie＇s disease have been gradually increased in recent years. Traction therapy can be employed as a solo therapy or a part of combination therapy, preoperative or postoperative therapy for Peyronie＇s disease. Recent researches show that traction therapy can prevent the progression of scar, restore the length and diameter of a short penis, reduce the curvature of the penis and improve sexual function. However, large sample, multi-center, randomized controlled studies are needed to confirm its validity for Peyronie＇s disease. In addition, more endeavors should be exerted at its pathogenesis in order to achieve effective prevention and cure of the disease.

关 键 词：阴茎硬结症 PEYRONIE病 牵引疗法 

分 类 号：R697[医药卫生—泌尿科学]