医学超声微泡造影剂空化效应的研究进展  

Progress of the mechanism and application on microbubbles and ultrasound mediated cavitation

作　　者：李立华[1] 曹军英[2] 王占江[2] 

机构地区：[1]大连医科大学 [2]辽宁省沈阳军区总医院特诊科

出　　处：《临床超声医学杂志》2014年第1期41-44,共4页Journal of Clinical Ultrasound in Medicine

基　　金：全军"十一.五"课题科技攻关项目(08G001)

摘　　要：近年来,随着新型超声微泡造影剂的研究和应用,超声微泡介导靶向治疗可增强基因转染效率,提高特定组织的基因表达水平和药物浓度,是一种安全、简便、高效的靶向性基因转染及药物治疗的新方法。本文就超声空化效应和超声微泡的治疗机制和应用做一简要综述。Recently, with the research and application of the new ultrasound microbubble contrast agents, microbubbles mediated ultrasound therapy has been used widely. The mierobubble mediated ultrasound therapy is a safe, convenient and effective method for target therapy, which helps to promote gene transfer efficiency,enhance gene expression and medicine concentration in targeted tissues. The mechanism and applications on ultrasonic cavitation and ultrasound contrast agents were reviewed in this paper.

关 键 词：超声空化 超声检查 造影剂 微泡 靶向治疗 

分 类 号：R445.1[医药卫生—影像医学与核医学]