脱细胞异体真皮基质填塞与切开挂线术治疗肛瘘的对比研究  

Comparative study of acellular extracellular matrix and incision plus thread drawing in the treatment of anal fistula

作　　者：林家威[1] 吴鸿根[1] 黄顺荣[1] 冯泽荣[1] 邓洪强[1] 潘云[1] 刘杨桦[1] 

机构地区：[1]广西壮族自治区人民医院普通外科,南宁市530021

出　　处：《微创医学》2013年第6期687-688,664,共3页Journal of Minimally Invasive Medicine

基　　金：广西壮族自治区卫生厅计划课题(合同号:Z2013364)

摘　　要：目的观察瘘管搔刮并脱细胞异体真皮基质填塞治疗肛瘘的临床疗效。方法将64例连续住院的肛瘘患者随机分为肛瘘瘘管搔刮并脱细胞异体真皮基质填塞术组(治疗组)和肛瘘切开挂线术组(对照组),比较两组术后伤口疼痛时间、愈合时间、愈合率、复发率、大便失禁、肛门畸形的情况。结果治疗组与对照组在愈合率、复发率、大便失禁率、肛门畸形率的比较,差异无统计学意义;两组在术后疼痛时间、愈合时间的比较,差异有统计学意义(P<0.05),治疗组优于对照组。结论瘘管搔刮并脱细胞异体真皮基质填塞治疗肛瘘是一种微创手术,术后疼痛轻、愈合快,可作为肛瘘治疗首选的方法。Objective To study the clinical efficacy of scraping fistula and acellular extracellular matrix in the treatment of anal fistula. Methods Sixty-four cases of consecutive hospitalized patients of anal fistula were randomly divided into two groups, one group treated with anal fistula scraping and acellular dermal matrix tamponade （treatment group, 32 cases） ,the other group treated with incision and thread drawing （the control group, 32cases ）. Postoperative pain time, healing time, healing rate, recurrence rate, fecal incontinence, and anal deformation were compared between the two groups. Results The difference was not statistically significant in healing rate, recurrence rate, fecal incontinence rate, or anal deformation between the two groups（P≥0.05 ）. The difference was statically significant in postoperative pain time and healing time between the two groups （P ≤ 0. 05 ）, with a superiority of treatment group over the control group. Conclusions A strategy involving anal fistula scraping and acellular dermal matrix tamponade is a minimally invasive surgery for anal fistula, with benefit of less pain and quick healing, indicating it as a first line treatment for patients with anal fistula.

关 键 词：肛瘘 脱细胞异体真皮基质 挂线术 

分 类 号：R657.1[医药卫生—外科学]