Effect of trabecular bone material properties on ultrasonic backscattering signals  

作　　者：LIU Chengcheng TA De'an WANG Weiqi 

机构地区：[1]Department of Electronic Engineering,Fudan University

出　　处：《Chinese Journal of Acoustics》2014年第1期73-82,共10页声学学报（英文版）

基　　金：supported by the National Natural Science Foundation of China(11174060,11327405);the Ph.D.Programs Foundation of the Ministry of Education of China(20110071130004,20130071110020);the Science and Technology Support Program of Shanghai(13441901900);the Program for New Century Excellent Talents in University(NCET-10-0349)

摘　　要：In this study, ultrasonic backscattering signals in cancellous bones were obtained by finite difference time domain （FDTD） simulations, and the effect of trabecular material properties on these signals was analyzed. The backscatter coefficient （BSC） and integrated backscatter coefficient （IBC） were numerically investigated for varying trabecular bone material properties, including density, Lame coefficients, viscosities, and resistance coefficients. The results show that the BSC is a complex function of trabecular bone density, and the IBC increases as density increases. The BSC and IBC increase with the first and second Lame coefficients. While not very sensitive to the second viscosity of the trabeculae, the BSC and IBC decrease as the first viscosity and resistance coefficients increase. The results demonstrate that, in addition to bone mineral density （BMD） and microarchitecture, trabecular material properties significantly influence ultrasonic backseattering signals in cancellous bones. This research furthers the understanding of ultrasonic backscattering in cancellous bones and the characterization of cancellous bone status.In this study, ultrasonic backscattering signals in cancellous bones were obtained by finite difference time domain （FDTD） simulations, and the effect of trabecular material properties on these signals was analyzed. The backscatter coefficient （BSC） and integrated backscatter coefficient （IBC） were numerically investigated for varying trabecular bone material properties, including density, Lame coefficients, viscosities, and resistance coefficients. The results show that the BSC is a complex function of trabecular bone density, and the IBC increases as density increases. The BSC and IBC increase with the first and second Lame coefficients. While not very sensitive to the second viscosity of the trabeculae, the BSC and IBC decrease as the first viscosity and resistance coefficients increase. The results demonstrate that, in addition to bone mineral density （BMD） and microarchitecture, trabecular material properties significantly influence ultrasonic backseattering signals in cancellous bones. This research furthers the understanding of ultrasonic backscattering in cancellous bones and the characterization of cancellous bone status.

关 键 词：bone Effect of trabecular bone material properties on ultrasonic backscattering signals BSC IBC FDTD 

分 类 号：R310[医药卫生—基础医学] TB559[理学—物理]