左卡尼汀对儿童病毒性心肌炎心率减速力的影响  

Effects of levocarnitine on deceleration capacity of heart rate in children with viral myocarditis

作　　者：顾坚[1] 张仕超[1] 鲍琼[1] 雷尚兵[1] 

机构地区：[1]湖北医药学院附属太和医院儿科,十堰442000

出　　处：《陕西医学杂志》2014年第1期27-29,共3页Shaanxi Medical Journal

摘　　要：目的:探讨左卡尼汀对儿童病毒性心肌炎(VMC)心率减速力(DC)的影响。方法:将40例病毒性心肌炎患儿设为治疗组,每天给予左卡尼汀100mg/kg,静脉滴注,疗程14d;对照组为30例健康体检儿童。对所有患儿在治疗前后以及对照组儿童进行24h动态心电图检查,应用DC处理软件,离线计算DC值。结果:治疗组治疗前DC值较对照组明显降低(P<0.05)。治疗后DC值有明显改善,与治疗前比较有显著性差异(P<0.05),与对照组比较无显著性差异(P>0.05)。结论:病毒性心肌炎患儿有迷走神经功能受损,左卡尼汀可改善迷走神经功能,对心肌有保护作用。Objective：To study the effect of Levocarnitine on deceleration capacity of heart rate in children with viral myocarditis. Methods：40 cases of children with viral myocarditis as the treatment group, treated with Le- vocarnitine injection（100mg/kg）,for 14 days;the control group of 30 healthy children. The DC in all patients before and after treatment and control group children was measured using digitized 24 hours ECG Holter recording. Re- sults：Compared with the control group, the treatment group before treatment,DC value decreased, the difference was statistically significant （P〈 0. 05）. After treatment, DC value was significantly improved, compared with before treatment, the difference was statistically significant （P〈0.05）,and the control group had no significant difference （P〈0.05）. Conclusion：It is suggested that there is vagus nerve damage in children with viral myocarditis,Levocar nitine can improve the vagus nerve function,and it has a protective effect on myocardial.

关 键 词：心肌炎 药物疗法 病毒性疾病 儿童 @左卡尼汀 

分 类 号：R725.4[医药卫生—儿科]